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Pimelic Acids

Known as: Acids, Pimelic, Pimelic Acids [Chemical/Ingredient] 
A group of compounds that are derivatives of heptanedioic acid with the general formula R-C7H11O4.
National Institutes of Health

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GM 53Pimelic Acidalpha-aminopimelic acidmaleylpyruvic acid
In Bloodagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

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2017
2017
Exploring sources of biogenic secondary organic aerosol compounds using chemical analysis and the FLEXPART model
Abstract. Molecular tracers in secondary organic aerosols (SOAs) can provide information on origin of SOA, as well as regional… 
2014
2014
Discovery of an orally active subtype-selective HDAC inhibitor, chidamide, as an epigenetic modulator for cancer treatment
Tumorigenesis is maintained through a complex interplay of multiple cellular biological processes and is regulated to some extent… 
2012
2012
Biodegradable polyesters reinforced with triclosan loaded polylactide micro/nanofibers: Properties, release and biocompatibility
Mechanical properties and drug release behavior were studied for three biodegradable polyester matrices (poly- caprolactone, poly… 
Highly Cited
2010
Highly Cited
2010
Two New Pimelic Diphenylamide HDAC Inhibitors Induce Sustained Frataxin Upregulation in Cells from Friedreich's Ataxia Patients and in a Mouse Model
Background Friedreich's ataxia (FRDA), the most common recessive ataxia in Caucasians, is due to severely reduced levels of… 
Highly Cited
2008
Highly Cited
2008
Pimelic Diphenylamide 106 Is a Slow, Tight-binding Inhibitor of Class I Histone Deacetylases*
Histone deacetylase (HDAC) inhibitors, including various benzamides and hydroxamates, are currently in clinical development for a… 
2005
2005
Azelaic and pimelic acids: Metabolic intermediates or artefacts?
SummaryAzelaic and pimelic acids are excreted in elevated amounts in urine in disorders of mitochondrial β-oxidation and… 
1989
1989
The "survival hormones": azelaic and pimelic acids, suppress the stress elicited by isolation conditions on the steroids and phospholipids of adult worker honeybees.
The kinetics of abdomen, haemolymph and thoracic-muscle steroid and phospholipid concentrations have been determined in adult… 
1988
1988
Formation of a biotin precursor, pimelic acid, in yeasts from C18 fatty acids.
The biosynthesis of biotin-vitamers from C18 fatty acids in the resting cell reaction system of yeasts was investigated. The… 
1968
1968
Agents for alkylating steroid hormone receptors. I. Analogs derived from esters of 17-alpha-hydroxyprogesterone.
1941
1941
Studies in detoxication: The metabolism of vanillin and vanillic acid in the rabbit. The identification of glucurovanillin and the structure of glucurovanillic acid.
WHEN aldehydes are fed to animals, the -CHO group is either reduced to -CH20H or oxidized to -COOH. It can be stated broadly that… 
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