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Pilocarpine

Known as: 2(3H)-Furanone, 3-ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-, (3S-cis)-, (3S,4R)-3-Ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-2(3H)-furanone, (3S-cis)-3-Ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone 
A natural alkaloid extracted from plants of the genus Pilocarpus with cholinergic agonist activity. As a cholinergic parasympathomimetic agent… 
National Institutes of Health

Related topics

Related topics

36 relations

Narrower (11)

3-hydroxypilocarpineBetoptic PiloGlauko-BicironIsoptocarpine

Broader (5)

AlkaloidsCholinergic AgentsGanglionic StimulantsMiotics
Angle Closure GlaucomaAsthmaDrug AllergyHead and Neck Neoplasms

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2001
2001
Salivary scintigraphy for assessing the protective effect of pilocarpine in head and neck irradiated tumours
Patients with head and neck cancers can develop salivary hypofunction after radiotherapy. The use of pilocarpine during… 
1984
1984
Quantitative evaluation of topically applied pilocarpine in the precorneal area.
The bioavailability of topically applied pilocarpine is poor due to various loss mechanisms that serve to lessen delivery of the… 
1981
1981
Quantitative determination of pilocarpine, isopilocarpine, pilocarpic acid, and isopilocarpic acid in clinical ophthalmic pilocarpine formulations by reversed-phase liquid chromatography.
A rapid and convenient reversed-phase high-performance liquid chromatographic procedure for the quantitative determination of… 
1977
1977
Pilocarpine stimulation of the bronchiolar Clara cell secretion.
  • K. Yoneda
  • Laboratory investigation; a journal of technical…
  • 1977
  • Corpus ID: 23338142
Fasted rats were given a single cholinergic subcutaneous injection of pilocarpine and sacrificed from 30 minutes to 24 hours… 
1976
1976
Pilocarpine ocular inserts.
Pilocarpine was administered to a selected group of ocular hypertensive subjects in the form of a synthetic biosoluble matrix… 
Highly Cited
1965
Highly Cited
1965
Comparison of rat salivas evoked by auriculo-temporal and pilocarpine stimulation.
Stimulation of rat parotid gland by way of the auriculotemporal nerve was used to delineate the relationship between flow rate… 
1965
1965
MERCURIAL PRESERVATIVES IN EYE-DROPS*
IT was reported recently by one of us (Abrams, 1963) that the long-term instillation of miotic drops preserved with… 
1957
1957
The action of histamine, pilocarpine and 5‐hydroxytryptamine on transmission through the superior cervical ganglion
Intra-arterial injections of histamine, pilocarpine and 5-hydroxytryptamine (5-HT) into the blood supply of the superior cervical… 
1949
1949
The nicotinic action of substances supposed to be purely smooth‐muscle stimulating
The quaternary iodide of c -,-ethylal-y-trimethylammonium-propanediol (2268F) was synthesized by Fourneau, Bovet, Bovet… 
1938
1938
SWEAT SECRETION IN MAN: III. CLINICAL OBSERVATIONS ON SWEATING PRODUCED BY PILOCARPINE AND MECHOLYL
In spite of considerable clinical and experimental work, the physiologic activities involved in sweating produced by pilocarpine…