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Physostigmine sulfate

National Institutes of Health

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Abnormalities, Drug-InducedAsthmaCardiovascular DiseasesDrug Allergy
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Highly Cited
2009
Highly Cited
2009
Human Arylacetamide Deacetylase Is a Principal Enzyme in Flutamide Hydrolysis
Flutamide, an antiandrogen drug, is widely used for the treatment of prostate cancer. The initial metabolic pathways of flutamide… 
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2004
2004
Effects of scopolamine, physostigmine and chlordiazepoxide on punished and extinguished water consumption in rats
It has been postulated that behavioral inhibition due to punishment or extinction may be mediated by brain acetylcholine, and… 
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Highly Cited
1994
Highly Cited
1994
NMDA receptor antagonists decrease GABA outflow from the septum and increase acetylcholine outflow from the hippocampus: a microdialysis study
The modulation of the septohippocampal cholinergic pathway by glutamatergic or GABAergic inputs was studied by monitoring the… 
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Highly Cited
1990
Highly Cited
1990
Cholinergic neurons of the pontomesencephalic tegmentum release acetylcholine in the basal nuclear complex of freely moving rats
Two major systems of cholinergic projection neurons are found within the centrum of the mammalian brain: the basal nuclear… 
1988
1988
Effects of physostigmine on shuttle avoidance in rats exposed prenatally to ethanol.
Shuttle avoidance performance following pretreatment with physostigmine was assessed in 85- to 100-day-old rats whose mothers… 
Highly Cited
1986
Highly Cited
1986
Pilocarpine and physostigmine attenuate spatial memory impairments produced by lesions of the nucleus basalis magnocellularis.
The effects of bilateral ibotenic acid-induced lesions of the nucleus basalis magnocellularis (nBM) on the acquisition and… 
1980
1980
Synergism of the toxicity of physostigmine and neostigmine by lithium or by a reserpine-like agent (Ro4-1284).
A single sublethal i.p. dose of lithium chloride (300 mg/kg or 7.1 meq/kg) followed 12 h later by an otherwise sublethal s.c… 
1975
1975
Blockade by morphine of acetylcholine release from the caudate nucleus in the mid-pontine pretrigeminal cat
Consonant with the findings that morphine increases brain acetylcholine concentration3,5,s,9,13,16, 21 and blocks its evoked… 
1970
1970
Resistance to various pesticides induced by catatoxic steroids.
  • H. Selye
  • Archives of environmental health
  • 1970
  • Corpus ID: 42780058
In the rat the toxic actions of various pesticides such as ethion, dioxathion (Navadel), EPN, azin-phosmethyl, and parathion are… 
1968
1968
Cholinergic agents related to para-sleep state in acute brain stem preparations.
Abstract The effects of intravenous injection of cholinergic or anticholinergic agents in inducing the PS state were studied in… 
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