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Brain dysmorphology in individuals with severe prenatal alcohol exposure.
Novel findings were that in FAS participants, white matter volumes were more affected than gray matter volumes in the cerebrum, and parietal lobes wereMore affected than temporal and occipital lobes, and the hippocampus was relatively preserved in Fas participants. Expand
Fetal Alcohol Spectrum Disorders: An Overview
A diagnostic goal is to recognize FAS as a disorder of brain rather than one of physical characteristics, highlighting the relationship between the two. Expand
Fetal Alcohol Spectrum Disorders: An Overview with Emphasis on Changes in Brain and Behavior
An overview of important issues that surround these disorders and the structural and neurobehavioral consequences associated with prenatal exposure to alcohol are presented and the prevalence of fetal alcohol spectrum disorders is described. Expand
Executive functioning in children with heavy prenatal alcohol exposure.
Deficits in executive functioning were observed in alcohol-exposed children with or without the diagnosis of FAS and in the absence of mental retardation, consistent with anecdotal and empirical reports of deficits in behavioral control and with neuroanatomical evidence of volumetric reductions in structures within the frontal-subcortical system in children with heavy prenatal alcohol exposure. Expand
A review of the neurobehavioral deficits in children with fetal alcohol syndrome or prenatal exposure to alcohol.
  • S. Mattson, E. Riley
  • Psychology, Medicine
  • Alcoholism, clinical and experimental research
  • 1 April 1998
The behavioral and cognitive effects of prenatal alcohol exposure are reviewed, with a focus on IQ, activity, attention, learning, memory, language, motor, and visuospatial abilities in children prenatally exposed to varying amounts of alcohol, including those with fetal alcohol syndrome. Expand
Evaluation of Psychopathological Conditions in Children With Heavy Prenatal Alcohol Exposure
The results suggest that fetal alcohol exposure should be considered a possible factor in the pathogenesis of childhood psychiatric disorders. Expand
Foetal Alcohol Spectrum Disorders and alterations in brain and behaviour.
Brain imaging, neurobehavioural and experimental studies demonstrate the devastating consequences of prenatal alcohol exposure on the developing central nervous system, identifying specific brain regions affected, the range of severity of effects and mechanisms involved, and the potential molecular mechanisms that underlie the neuroteratological effects of alcohol. Expand
Abnormal cortical thickness and brain-behavior correlation patterns in individuals with heavy prenatal alcohol exposure.
It is shown that cortical thickness is also increased in right lateral frontal regions in children with prenatal alcohol exposure, and for the first time, that brain-behavior relationships are altered as a function of heavy prenatal alcohol Exposure. Expand
Teratogenic Effects of Alcohol on Brain and Behavior
Brain imaging studies have identified structural changes in various brain regions of these children—including the basal ganglia, corpus callosum, cerebellum, and hippocampus—that may account for the cognitive deficits. Expand
Characterization of white matter microstructure in fetal alcohol spectrum disorders.
Prenatal alcohol exposure was associated with low FA in multiple cerebral areas, including the body of the corpus callosum and white matter innervating bilateral medial frontal and occipital lobes, and support extant literature showing that white matter is a target of alcohol teratogenesis. Expand