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Phosphorylated Tau Protein Measurement

Known as: Phosphorylated Tau Protein, TPROTP 
The determination of the amount of phosphorylated Tau protein present in a sample.
National Institutes of Health

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3 relations
CDISC SDTM Laboratory Test Terminology by CodeCDISC SDTM Laboratory Test Terminology by NameClinical Data Interchange Standards Consortium Terminology

Papers overview

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Highly Cited
2017
Highly Cited
2017
ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy
APOE4 is the strongest genetic risk factor for late-onset Alzheimer disease. ApoE4 increases brain amyloid-β pathology relative… Expand
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Highly Cited
2015
Highly Cited
2015
Antibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathy
Traumatic brain injury (TBI), characterized by acute neurological dysfunction, is one of the best known environmental risk… Expand
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Review
2010
Review
2010
Total and phosphorylated tau protein as biological markers of Alzheimer’s disease
Advances in our understanding of tau-mediated neurodegeneration in Alzheimer's disease (AD) are moving this disease pathway to… Expand
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Highly Cited
2009
Highly Cited
2009
Cerebrospinal fluid {beta}-amyloid 42 and tau proteins as biomarkers of Alzheimer-type pathologic changes in the brain.
BACKGROUND There is a clear need to develop an objective diagnostic test for Alzheimer disease (AD). Changes in the levels of… Expand
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Highly Cited
2009
Highly Cited
2009
The unfolded protein response is activated in pretangle neurons in Alzheimer's disease hippocampus.
Accumulation of misfolded proteins in the endoplasmic reticulum triggers a cellular stress response called the unfolded protein… Expand
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Highly Cited
2006
Highly Cited
2006
CSF phosphorylated tau protein correlates with neocortical neurofibrillary pathology in Alzheimer's disease.
Hyperphosphorylated tau protein (P-tau) in CSF is a core biomarker candidate of Alzheimer's disease. Hyperphosphorylation of tau… Expand
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Review
2003
Review
2003
CSF markers for incipient Alzheimer's disease
Early diagnosis of Alzheimer's disease (AD) is needed to initiate symptomatic treatment with acetylcholinesterase inhibitors, and… Expand
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Highly Cited
2003
Highly Cited
2003
Biochemical diagnosis of Alzheimer disease by measuring the cerebrospinal fluid ratio of phosphorylated tau protein to beta-amyloid peptide42.
BACKGROUND The antemortem diagnosis of Alzheimer disease (AD) requires time-consuming and costly procedures. Therefore… Expand
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Highly Cited
2002
Highly Cited
2002
Amyloid β peptide induces tau phosphorylation and loss of cholinergic neurons in rat primary septal cultures
The neuropathological features associated with Alzheimer's disease (AD) brain include the presence of extracellular neuritic… Expand
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Highly Cited
1999
Highly Cited
1999
The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein
One of the neuropathological hallmarks of Alzheimer's disease is the neurofibrillary tangle, which contains paired helical… Expand
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