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Phosphorylated Epidermal Growth Factor Receptor
Known as:
pEGFR
, Epidermal growth factor receptor.phosphorylated
, Phosphorylated EGFR
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Epidermal growth factor receptor protein (EGFR) bearing phosphorylated tyrosine residues within the 194 amino acids of the carboxyl-terminal…
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Association of p16INK4a overexpression with improved outcomes in young patients with squamous cell cancers of the oral tongue
S. L. Harris
,
L. Thorne
,
W. Seaman
,
D. Neil Hayes
,
M. Couch
,
R. Kimple
Head and Neck
2011
Corpus ID: 25103580
The aim of this study was to examine biomolecular profiles in a cohort of young adults with squamous cell cancers (SCCs) of the…
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Highly Cited
2011
Highly Cited
2011
Alternative HER/PTEN/Akt Pathway Activation in HPV Positive and Negative Penile Carcinomas
E. Stankiewicz
,
D. Prowse
,
+8 authors
D. Berney
PLoS ONE
2011
Corpus ID: 7166389
Background The pathogenesis of penile squamous cell carcinoma (PSCC) is not well understood, though risk factors include human…
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Highly Cited
2011
Highly Cited
2011
Apoptosis Inducing Effect of Plumbagin on Colonic Cancer Cells Depends on Expression of COX-2
Bharathi Raja Subramaniya
,
G. Srinivasan
,
+4 authors
Niranjali Devaraj Sivasitambaram
PLoS ONE
2011
Corpus ID: 3885539
Plumbagin, a quinonoid found in the plants of the Plumbaginaceae, possesses medicinal properties. In this study we investigated…
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Highly Cited
2010
Highly Cited
2010
Retinoic acid regulates bone morphogenic protein signal duration by promoting the degradation of phosphorylated Smad1
Nengyin Sheng
,
Zhihui Xie
,
+8 authors
N. Jing
Proceedings of the National Academy of Sciences…
2010
Corpus ID: 32555733
The proper function of the bone morphogenic protein (BMP) pathway during embryonic development and organ maintenance requires its…
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Highly Cited
2008
Highly Cited
2008
Expression of the epidermal growth factor receptor (EGFR) and the phosphorylated EGFR in invasive breast carcinomas
C. Magkou
,
L. Nakopoulou
,
+4 authors
I. Giannopoulou
Breast Cancer Research
2008
Corpus ID: 11021437
IntroductionEpidermal growth factor receptor (EGFR) is involved in regulating cell growth in breast carcinomas. Its activated…
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Highly Cited
2008
Highly Cited
2008
A new role for tamoxifen in oestrogen receptor-negative breast cancer when it is combined with epigallocatechin gallate
MJ Scandlyn
,
EC Stuart
,
TJ Somers-Edgar
,
AR Menzies
,
RJ Rosengren
British Journal of Cancer
2008
Corpus ID: 13593743
We have previously shown that tamoxifen+epigallocatechin gallate (EGCG) is synergistically cytotoxic towards oestrogen receptor…
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Highly Cited
2006
Highly Cited
2006
Chemotherapy-induced epidermal growth factor receptor activation determines response to combined gefitinib/chemotherapy treatment in non–small cell lung cancer cells
S. Van Schaeybroeck
,
J. Kyula
,
+5 authors
P. Johnston
Molecular Cancer Therapeutics
2006
Corpus ID: 22255192
Activating epidermal growth factor receptor (EGFR) mutations have been linked with sensitivity to gefitinib and erlotinib…
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Highly Cited
1999
Highly Cited
1999
Adenylyl Cyclase Activation Modulates Activity-Dependent Changes in Synaptic Strength and Ca2+/Calmodulin-Dependent Kinase II Autophosphorylation
M. Makhinson
,
Jennifer K. Chotiner
,
J. Watson
,
T. O’Dell
Journal of Neuroscience
1999
Corpus ID: 1032481
Activation of the Ca2+- and calmodulin-dependent protein kinase II (CaMKII) and its conversion into a persistently activated form…
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Highly Cited
1992
Highly Cited
1992
Systematic mutational analysis of cAMP-dependent protein kinase identifies unregulated catalytic subunits and defines regions important for the recognition of the regulatory subunit.
C. Gibbs
,
D. Knighton
,
J. Sowadski
,
S. Taylor
,
M. Zoller
Journal of Biological Chemistry
1992
Corpus ID: 25268786
Highly Cited
1987
Highly Cited
1987
Direct visualization of the phosphorylated epidermal growth factor receptor during its internalization in A-431 cells
L. Orci
Journal of Cell Biology
1987
Corpus ID: 20784991
Epidermal growth factor (EGF) rapidly stimulates receptor autophosphorylation in A-431 cells. After 1 min the phosphorylated…
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