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WHO Classification of of Tumours of the Urinary System and Male Genital Organs
TLDR
This document is intended to assist in the preparation of future studies on how to integrate Python into the e-commerce system. Expand
Prognostic value of an RNA expression signature derived from cell cycle proliferation genes in patients with prostate cancer: a retrospective study.
TLDR
There is strong evidence that the CCP score is a robust prognostic marker, which, after additional validation, could have an essential role in determining the appropriate treatment for patients with prostate cancer. Expand
Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer
TLDR
It is concluded that determination of ERG gene status, including duplication of the fusion of TMPRSS2 to ERG sequences in 2+Edel, allows stratification of prostate cancer into distinct survival categories. Expand
Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer
TLDR
This study analyzed somatic alterations in mtDNA from 1675 tumors and identified 1907 somatic substitutions, which exhibited dramatic replicative strand bias, predominantly C > T and A > G on the mitochondrial heavy strand. Expand
The role of the aryl hydrocarbon receptor-interacting protein gene in familial and sporadic pituitary adenomas.
TLDR
The abnormal expression and subcellular localization of AIP in sporadic pituitary adenomas indicate deranged regulation of this protein during tumorigenesis. Expand
Prognostic value of a cell cycle progression signature for prostate cancer death in a conservatively managed needle biopsy cohort
TLDR
For conservatively managed patients, the CCP score is the strongest independent predictor of cancer death outcome yet described and may prove valuable in managing clinically localised prostate cancer. Expand
Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer
TLDR
The data suggest that FISH studies of PTEN gene loss and ERG/ETV1 gene rearrangements could be pursued for patient stratification, selection and hypothesis-generating subgroup analyses in future PCa clinical trials and potentially in patient management. Expand
Heterogeneity and clinical significance of ETV1 translocations in human prostate cancer
TLDR
In 5′-RACE experiments on RNA extracted from formalin-fixed tissue, the androgen-upregulated gene ACSL3 is identified as a new 5-translocation partner of ETV1 and these studies report a novel fusion partner for ETV2 and highlight the considerable heterogeneity of E TV1 gene rearrangements in human prostate cancer. Expand
Fumarate Hydratase–deficient Renal Cell Carcinoma Is Strongly Correlated With Fumarate Hydratase Mutation and Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome
TLDR
It is concluded that FH and 2SC are useful IHC ancillary tools, which allow recognition of FH-deficient RCC. Expand
The outcome of patients treated with sunitinib prior to planned nephrectomy in metastatic clear cell renal cancer.
TLDR
Upfront sunitinib prior to planned nephrectomy in intermediate-risk disease is associated with a median survival of >2 yr despite frequent progression during treatment break, and progression in metastatic sites prior toplanned surgery and MSKCC poor- risk disease was associated withA poor outcome. Expand
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