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Phosphonoacetic Acid

Known as: Acetic acid, phosphono-, PPA, Phosphonacetic Acid 
An antiviral agent with activity against herpes simplex viruses and other members of the herpes virus family. Phosphonoacetic acid inhibits viral DNA… 
National Institutes of Health

Related topics

Related topics

19 relations

Narrower (9)

6-methacryloyloxyhexyl phosphonoacetateDisodium PhosphonoacetateFoscarnetPhosphonoacetate

Broader (3)

Antiviral AgentsEnzyme InhibitorsReverse Transcriptase Inhibitors
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Biohybrid block copolymers: towards functional micelles and vesicles.
This critical review covers the elaboration of micelles and vesicles made from block copolymers containing peptide or… 
Highly Cited
2001
Highly Cited
2001
Properties of the prophenoloxidase activating enzyme of the freshwater crayfish, Pacifastacus leniusculus.
The prophenoloxidase activating enzyme (ppA), a serine proteinase catalyzing the conversion of prophenoloxidase to an active… 
Highly Cited
1995
Highly Cited
1995
Carbohydrate binding sites in a pancreatic α‐amylase‐substrate complex, derived from X‐ray structure analysis at 2.1 Å resolution
The X‐ray structure analysis of a crystal of pig pancreatic α‐amylase (PPA, EC 3.2.1.1.) that was soaked with the substrate… 
Highly Cited
1983
Highly Cited
1983
Characterization of human cytomegalovirus-induced DNA polymerase and the associated 3'-to-5', exonuclease.
Highly Cited
1980
Highly Cited
1980
Resistance of herpes simplex virus to acycloguanosine--genetic and physical analysis.
Highly Cited
1979
Highly Cited
1979
Acyclovir in Oral and Ganglionic Herpes Simplex Virus Infections
The local and trigeminal ganglionic therapeutic efficacy of two topical and systemic antiviral drugs was studied in mouse lips… 
Highly Cited
1978
Highly Cited
1978
Toxicological studies on pipemidic acid. V. Effect on diarthrodial joints of experimental animals.
Pipemidic acid (PPA) orally given in a dose of 100 mg/kg/day or more was found to cause lame gait in immature beagle dogs of… 
Highly Cited
1977
Highly Cited
1977
Genetics of resistance to phosphonoacetic acid in strain KOS of herpes simplex virus type 1
A DNA- temperature-sensitive mutant of herpes simplex virus type 1 exhibiting thermolabile DNA polymerase activity, tsD9, was… 
Highly Cited
1976
Highly Cited
1976
Inhibition of Epstein-Barr virus DNA synthesis and late gene expression by phosphonoacetic acid
Growth of lymphoblastoid cells (B95-8, Raji) is not inhibited by the presence of 0.4 mM phosphonoacetic acid. The synthesis of… 
Highly Cited
1975
Highly Cited
1975
Synthesis of herpes simplex virus, vaccinia virus, and adenovirus DNA in isolated HeLa cell nuclei. I. Effect of viral-specific antisera and phosphonoacetic acid
Purified nuclei, isolated from appropriately infected HeLa cells, are shown to synthesize large amounts of either herpes simplex… 
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