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Phospholipase C beta

Known as: PLC beta, Phospholipase C beta [Chemical/Ingredient], Phospholipase C-beta 
A phosphoinositide phospholipase C subtype that is primarily regulated by its association with HETEROTRIMERIC G-PROTEINS. It is structurally related… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Background Although evidence points to a role for histamine and serotonin in visceral hypersensitivity, activation of calcium… Expand
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Highly Cited
2009
Highly Cited
2009
Breast cancer is the most frequent form of cancer in women, with the highest incidence of metastasis to the bone. The reason for… Expand
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Review
2007
Review
2007
Endogenous cannabinoids (endocannabinoids) serve as retrograde messengers at synapses in various regions of the brain. They are… Expand
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Highly Cited
2006
Highly Cited
2006
Phospholipase Cbeta (PLCbeta) isozymes represent a family of molecules that link G protein-coupled receptors (GPCRs) to an… Expand
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Highly Cited
1998
Highly Cited
1998
Cardiac hypertrophy and dilatation can result from stimulation of signal transduction pathways mediated by heterotrimeric G… Expand
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Highly Cited
1998
Highly Cited
1998
Ligand binding to neurotransmitter and hormone receptors which couple to the Gq subclass of GTP‐binding protein leads to the… Expand
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Highly Cited
1997
Highly Cited
1997
RGS proteins constitute a newly appreciated and large group of negative regulators of G protein signaling. Four members of the… Expand
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Highly Cited
1994
Highly Cited
1994
The beta-subunits of the heterotrimeric GTP-binding proteins (G-proteins) are important regulators of G-protein alpha-subunits as… Expand
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Highly Cited
1992
Highly Cited
1992
Purified M1 muscarinic cholinergic receptor and Gq/11 were coreconstituted in lipid vesicles. Addition of purified phospholipase… Expand
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Highly Cited
1992
Highly Cited
1992
High efficiency transient transfection of Cos-7 cells was previously used to establish the functional coupling between G alpha q… Expand
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