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Phospholipase C beta1

Known as: PLC beta1, Phospholipase C-beta1 
 
National Institutes of Health

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Phospholipase C beta

Papers overview

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2009
2009
Involvement of nuclear PLCβl in lamin B1 phosphorylation and G2/M cell cycle progression
Inositide‐specific phospholipase Cβ1 (PLCβ1) signaling in cell proliferation has been investigated thoroughly in the G1 cell… Expand
Highly Cited
2009
Highly Cited
2009
TRPC Channels Mediate a Muscarinic Receptor-Induced Afterdepolarization in Cerebral Cortex
Activation of muscarinic cholinergic receptors on pyramidal cells of the cerebral cortex induces the appearance of a slow… Expand
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2008
2008
The extreme C‐terminal region of phospholipase Cβ1 determines subcellular localization and function; the “b” splice variant mediates α1‐adrenergic receptor responses in cardiomyocytes
Phospholipase Cβ1 (PLCβ1) exists as two splice variants, PLCβ1a (150 kDa) and PLCβ1b (140 kDa), which differ only in their C… Expand
Highly Cited
2005
Highly Cited
2005
Phospholipase Cβ Serves as a Coincidence Detector through Its Ca2+ Dependency for Triggering Retrograde Endocannabinoid Signal
Endocannabinoids mediate retrograde signal and modulate transmission efficacy at various central synapses. Although… Expand
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Highly Cited
2005
Highly Cited
2005
Impaired metabotropic glutamate receptor/phospholipase C signaling pathway in the cerebral cortex in Alzheimer's disease and dementia with Lewy bodies correlates with stage of Alzheimer's-disease…
The aim of the present work was to analyze the status of metabotropic glutamate receptors (mGluRs) in the frontal cortex (area 8… Expand
2003
2003
Diacylglycerol kinase-theta is localized in the speckle domains of the nucleus.
It is well established that the nucleus is endowed with enzymes that are involved in lipid-dependent signal transduction pathways… Expand
2002
2002
Phosphatidylinositol 4,5-Bisphosphate Modifies Tubulin Participation in Phospholipase Cβ1 Signaling
Tubulin forms the microtubule and regulates certain G-protein-mediated signaling pathways. Both functions rely on the GTP-binding… Expand
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Highly Cited
2002
Highly Cited
2002
Role of synaptic metabotropic glutamate receptors in epileptiform discharges in hippocampal slices.
Application of group I metabotropic glutamate receptor (mGluR) agonists elicits seizure discharges in vivo and prolonged ictal… Expand
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2002
2002
Phosphatidylinositol 4,5-bisphosphate modifies tubulin participation in phospholipase Cbeta1 signaling.
Tubulin forms the microtubule and regulates certain G-protein-mediated signaling pathways. Both functions rely on the GTP-binding… Expand
Highly Cited
1999
Highly Cited
1999
Metabotropic Glutamate Receptor-Mediated Hippocampal Phosphoinositide Turnover Is Blunted in Spatial Learning-Impaired Aged Rats
Maximal phosphoinositide (PI) turnover was examined in the hippocampus of young and aged Long–Evans rats that were behaviorally… Expand
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