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Phospholipase C beta1

Known as: PLC beta1, Phospholipase C-beta1 
 
National Institutes of Health

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Phospholipase C beta

Papers overview

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2009
2009
Involvement of nuclear PLCbeta1 in lamin B1 phosphorylation and G2/M cell cycle progression.
Inositide-specific phospholipase Cbeta1 (PLCbeta1) signaling in cell proliferation has been investigated thoroughly in the G(1… Expand
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Highly Cited
2009
Highly Cited
2009
TRPC Channels Mediate a Muscarinic Receptor-Induced Afterdepolarization in Cerebral Cortex
Activation of muscarinic cholinergic receptors on pyramidal cells of the cerebral cortex induces the appearance of a slow… Expand
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2008
2008
The extreme C-terminal region of phospholipase Cbeta1 determines subcellular localization and function; the "b" splice variant mediates alpha1-adrenergic receptor responses in cardiomyocytes.
Phospholipase Cbeta1 (PLCbeta1) exists as two splice variants, PLCbeta1a (150 kDa) and PLCbeta1b (140 kDa), which differ only in… Expand
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Highly Cited
2005
Highly Cited
2005
Impaired metabotropic glutamate receptor/phospholipase C signaling pathway in the cerebral cortex in Alzheimer's disease and dementia with Lewy bodies correlates with stage of Alzheimer's-disease…
The aim of the present work was to analyze the status of metabotropic glutamate receptors (mGluRs) in the frontal cortex (area 8… Expand
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Highly Cited
2005
Highly Cited
2005
Phospholipase Cβ Serves as a Coincidence Detector through Its Ca2+ Dependency for Triggering Retrograde Endocannabinoid Signal
Endocannabinoids mediate retrograde signal and modulate transmission efficacy at various central synapses. Although… Expand
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2003
2003
Diacylglycerol kinase-theta is localized in the speckle domains of the nucleus.
It is well established that the nucleus is endowed with enzymes that are involved in lipid-dependent signal transduction pathways… Expand
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2002
2002
Phosphatidylinositol 4,5-bisphosphate modifies tubulin participation in phospholipase Cbeta1 signaling.
Tubulin forms the microtubule and regulates certain G-protein-mediated signaling pathways. Both functions rely on the GTP-binding… Expand
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2002
2002
Phosphatidylinositol 4,5-Bisphosphate Modifies Tubulin Participation in Phospholipase Cβ1 Signaling
Tubulin forms the microtubule and regulates certain G-protein-mediated signaling pathways. Both functions rely on the GTP-binding… Expand
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2002
2002
Role of synaptic metabotropic glutamate receptors in epileptiform discharges in hippocampal slices.
Application of group I metabotropic glutamate receptor (mGluR) agonists elicits seizure discharges in vivo and prolonged ictal… Expand
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1999
1999
Metabotropic Glutamate Receptor-Mediated Hippocampal Phosphoinositide Turnover Is Blunted in Spatial Learning-Impaired Aged Rats
Maximal phosphoinositide (PI) turnover was examined in the hippocampus of young and aged Long–Evans rats that were behaviorally… Expand
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