Phenytoin

Known as: Phenytoin [Chemical/Ingredient], Phentytoin, Fenitoina 
An anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Phenytoin is an 80-year young molecule and new indications are still emerging. The neuroprotective potential of phenytoin has… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE Previous studies found a strong association between HLA-B*1502 and carbamazepine (CBZ)-induced Stevens-Johnson syndrome… (More)
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Highly Cited
2005
Highly Cited
2005
Phenytoin and carbamazepine are effective and inexpensive anti-epileptic drugs (AEDs). As with many AEDs, a broad range of doses… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Seizures occur in 1 to 2 percent of neonates admitted to an intensive care unit. The treatment is usually with either… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND AND METHODS Although generalized convulsive status epilepticus is a life-threatening emergency, the best initial drug… (More)
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Highly Cited
1996
Highly Cited
1996
The mouse mdr1a (also called mdr3) P-GP is abundant in the blood-brain barrier, and its absence in mdr1a (-/-) mice leads to… (More)
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Highly Cited
1992
Highly Cited
1992
OBJECTIVES The objectives of this study were to present data on eight patients with recurrent episodes of aborted sudden death… (More)
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Highly Cited
1990
Highly Cited
1990
BACKGROUND Antiepileptic drugs are commonly used to prevent seizures that may follow head trauma. However, previous controlled… (More)
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Highly Cited
1989
Highly Cited
1989
0 27. With hypertonic peritoneal dialysis his weight decreased by 1 6 kg, but blood pressure remained raised at 230/130 mm Hg… (More)
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Highly Cited
1985
Highly Cited
1985
We conducted a 10-center, double-blind trial to compare the efficacy and toxicity of four antiepileptic drugs in the treatment of… (More)
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