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Phenytoin

Known as: Phenytoin [Chemical/Ingredient], Phentytoin, Fenitoina 
An anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic… 
National Institutes of Health

Related topics

Related topics

42 relations
2 ML Fosphenytoin sodium 75 MG/ML InjectionAntiepileptic AgentsCYP2C19 protein, humanCYP2C9 protein, human

Narrower (11)

2-cyanoguanidinophenytoin3-(hydroxymethyl)phenytoin3-pentanoyl-5,5-diphenylhydantoinEpamin

Broader (4)

AnticonvulsantsCytochrome P-450 CYP1A2 InducersHydantoin derivative anticonvulsantVoltage-Gated Sodium Channel Blockers

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1987
Highly Cited
1987
Lamotrigine: single-dose pharmacokinetics and initial 1 week experience in refractory epilepsy
Highly Cited
1987
Highly Cited
1987
Fluorescence lifetime distributions of 1,6-diphenyl-1,3,5-hexatriene in phospholipid vesicles.
The fluorescence emission properties of 1,6-diphenyl-1,3,5-hexatriene (DPH) in 1,2-dipalmitoyl-3-sn-phosphatidylcholine and 1,2… 
Review
1982
Review
1982
The effect of various centrally active drugs on adenosine uptake by the central nervous system.
  • J. PhillisP. Wu
  • Comparative biochemistry and physiology. C…
  • 1982
  • Corpus ID: 23155221
Highly Cited
1981
Highly Cited
1981
Values for and significance of order parameters and "cone angles" of fluorophore rotation in lipid bilayers.
A rigid formalism has been developed for the calculation of the order parameter S for fluorescence probes embedded in… 
Highly Cited
1972
Highly Cited
1972
Studies on dexamethasone metabolism in man: effect of diphenylhydantoin.
Plasma kinetics and metabolism of labeled dexamethasone were evaluated in nine subjects before and after administration of… 
Highly Cited
1970
Highly Cited
1970
Quantitative estimation of diphenylhydantoin, primidone and phenobarbital in plasma by gas-liquid chromatography.
  • H. Kupferberg
  • Clinica chimica acta; international journal of…
  • 1970
  • Corpus ID: 34246013
Highly Cited
1969
Highly Cited
1969
The Developing Animal as a Model
Evidence is presented that some excitatory systems are mature at birth and that inhibitory systems develop rapidly during the… 
Highly Cited
1967
Highly Cited
1967
Peripheral neuropathy in long-term diphenylhydantoin therapy.
SINCE the introduction of diphenylhydantoin by Merritt and Putnam 1 in 1938, it has been the drug of choice in the treatment of… 
Highly Cited
1965
Highly Cited
1965
Diphenylhydantoin activated seizures
EXCESSIVE intake of many common anticonvulsant drugs may result in symptoms of central nervous system intoxication. It is the… 
Highly Cited
1963
Highly Cited
1963
Determination of diphenylhydantoin and phenobarbital in small amounts of serum.
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