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Phenprocoumon

Known as: Phenylpropylhydroxycumarinum, 4-Hydroxy-3-(1-phenylpropyl)-2H-1-benzopyran-2-one, 3-(alpha-Phenylpropyl)-4-hydroxycoumarin 
An orally available, long-acting derivative of coumarin with anticoagulant activity. Upon administration, phenprocoumon inhibits the vitamin K… 
National Institutes of Health

Related topics

Related topics

43 relations

Narrower (7)

2'-hydroxyphenprocoumon4'-hydroxyphenprocoumon6-hydroxyphenprocoumon7-hydroxyphenprocoumon
Alcoholic Intoxication, ChronicAneurysmAscorbic Acid DeficiencyBacterial Endocarditis

Broader (1)

Anticoagulants

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Does the number of simultaneously activated electrodes during phased RF multielectrode ablation of atrial fibrillation influence the incidence of silent cerebral microembolism?
Review
2006
Review
2006
Oral anticoagulation therapy in children.
Highly Cited
2004
Highly Cited
2004
The risk of overanticoagulation in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol or phenprocoumon.
Cytochrome P4502C9 (CYP2C9) is the main enzyme implicated in coumarin anticoagulant metabolism. The variant alleles CYP2C9*2 and… 
Highly Cited
2004
Highly Cited
2004
Identification of cytochromes P450 2C9 and 3A4 as the major catalysts of phenprocoumon hydroxylation in vitro
ObjectiveThis in-vitro study aimed at an identification of cytochrome P450 (CYP) enzymes catalysing the (S)- and (R… 
Highly Cited
2003
Highly Cited
2003
Determination of bleeding risk using genetic markers in patients taking phenprocoumon
BackgroundIn patients on oral anticoagulation with warfarin, genetic variations of the cytochrome P 450–CYP2C9 have recently been… 
1998
1998
Detection of 4-hydroxycoumarin anticoagulants and their metabolites in urine as part of a systematic toxicological analysis procedure for acidic drugs and poisons by gas chromatography-mass…
1994
1994
In vitro model to test the thrombogenicity of coronary stents.
Highly Cited
1988
Highly Cited
1988
INFLUENCE OF POSTOPERATIVE ANTICOAGULANT TREATMENT ON PATIENT SURVIVAL AFTER FEMOROPOPLITEAL VEIN BYPASS SURGERY
Highly Cited
1988
Highly Cited
1988
Decreased serum osteocalcin levels in phenprocoumon-treated patients.
Osteocalcin (OC) is a noncollagenous bone matrix protein containing gamma-carboxyglutamic acid, the synthesis of which is vitamin… 
1975
1975
Synthesis and thin-layer chromatographic ultraviolet, and mass spectral properties of the anticoagulant phenprocoumon and its monohydroxylated derivatives.
Phenprocoumon and all of its aromatic monohydroxylated derivatives have been synthesized and analyzed by TLC, uv, and chemical… 
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