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Pertussis Toxin

Known as: Islet Activating Protein, IAP Pertussis Toxin, Pertussigen 
A class of biologically active protein toxins expressed by Bordetella pertussis, which causes the symptoms of whooping cough. Following bacterial… Expand
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
A more virulent strain of the disease is emerging. 
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Highly Cited
1999
Highly Cited
1999
Background—β-Adrenergic receptor (β-AR) stimulation increases apoptosis in adult rat cardiac (ventricular) myocytes (ARVMs) via… Expand
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Highly Cited
1999
Highly Cited
1999
Defensins contribute to host defense by disrupting the cytoplasmic membrane of microorganisms. This report shows that human beta… Expand
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Highly Cited
1998
Highly Cited
1998
Vaccine efficacies against typical pertussis after household exposure to Bordetella pertussis were estimated to be 75.4% for an… Expand
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Highly Cited
1998
Highly Cited
1998
ABSTRACT The Bordetella pertussis proteins P.69 (also designated pertactin) and pertussis toxin are important virulence factors… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Concern about both safety and efficacy has made the use of whole-cell pertussis vaccines controversial. In some… Expand
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Highly Cited
1996
Highly Cited
1996
Mast cells are known to accumulate at sites of inflammation, however, the chemotaxins involved are undefined. Since most natural… Expand
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Highly Cited
1995
Highly Cited
1995
Recently we demonstrated that the effects of beta 2-adrenoceptor (AR) stimulation to augment Ca2+ current (ICa), cytosolic Ca2… Expand
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Highly Cited
1988
Highly Cited
1988
Human heart failure is associated with a diminished contractile response to beta-adrenergic agonists. We hypothesized that… Expand
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Highly Cited
1986
Highly Cited
1986
ADP-ribosylation of regulatory proteins is an important pathological mechanism by which various bacterial toxins affect eukary… Expand
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