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Pertussis Toxin

Known as: Islet Activating Protein, IAP Pertussis Toxin, Pertussigen 
A class of biologically active protein toxins expressed by Bordetella pertussis, which causes the symptoms of whooping cough. Following bacterial… 
National Institutes of Health

Related topics

Related topics

12 relations

Broader (1)

Bacterial Toxins
Bordetella pertussisIn BloodProcess of secretionVirulence Factors, Bordetella

Papers overview

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Highly Cited
2001
Highly Cited
2001
HIV-1 gp120 and chemokine activation of Pyk2 and mitogen-activated protein kinases in primary macrophages mediated by calcium-dependent, pertussis toxin-insensitive chemokine receptor signaling.
Human immunodeficiency virus type 1 (HIV-1) uses the chemokine receptors CCR5 and CXCR4 as coreceptors for entry. It was recently… 
Highly Cited
1994
Highly Cited
1994
C3a activates the respiratory burst in human polymorphonuclear neutrophilic leukocytes via pertussis toxin-sensitive G-proteins.
In contrast to C5a, which represents a well-established potent activator of the respiratory burst in polymorphonuclear… 
Highly Cited
1991
Highly Cited
1991
Calcium signaling capacity of the CD11b/CD18 integrin on human neutrophils.
Highly Cited
1991
Highly Cited
1991
Purification and characterization of two G-proteins that activate the beta 1 isozyme of phosphoinositide-specific phospholipase C. Identification as members of the Gq class.
Highly Cited
1989
Highly Cited
1989
Tyrosine phosphorylation in human neutrophil.
Highly Cited
1988
Highly Cited
1988
Sequence analysis of cDNA and genomic DNA for a putative pertussis toxin-insensitive guanine nucleotide-binding regulatory protein alpha subunit.
We have isolated cDNA clones from rat C6 glioma cells coding for several guanine nucleotide-binding regulatory protein (G protein… 
Highly Cited
1986
Highly Cited
1986
Hormone-stimulated polyphosphoinositide breakdown in rat liver plasma membranes. Roles of guanine nucleotides and calcium.
Calcium-sensitive inositide release in a purified rat liver plasma membrane preparation is increased by calcium-mobilizing… 
Highly Cited
1985
Highly Cited
1985
Potential role for a guanine nucleotide regulatory protein in chemoattractant receptor mediated polyphosphoinositide metabolism, Ca++ mobilization and cellular responses by leukocytes.
Highly Cited
1984
Highly Cited
1984
ADP-ribosylation of the specific membrane protein by islet-activating protein, pertussis toxin, associated with inhibition of a chemotactic peptide-induced arachidonate release in neutrophils. A…
Guinea pig neutrophils were maintained for 4 h in culture medium containing [3H]arachidonic acid for the purpose of labeling… 
Highly Cited
1983
Highly Cited
1983
Pertussis toxin substrate, the putative Ni component of adenylyl cyclases, is an alpha beta heterodimer regulated by guanine nucleotide and magnesium.
The final step in a scheme for the purification of the guanine nucleotide- and Mg2+-binding stimulatory regulatory component (Ns… 
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