Peroxisome Biogenesis Disorder, Complementation Group K
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From the early periods of neurogenesis and migration, up until synaptogenesis, both nitric oxide (NO) and its downstream… Expand Signalling of cGK (cGMP-dependent protein kinases) are mediated through phosphorylation of specific substrates. Several… Expand Recent results suggest that long-lasting potentiation at hippocampal synapses involves the rapid formation of clusters or puncta… Expand Type II cGMP-dependent protein kinase (cGK II) is the protein product of one of two genes coding for cGKs in mammalian genomes… Expand Amyloid-beta (Abeta), a peptide thought to play a crucial role in Alzheimer's disease (AD), has many targets that, in turn… Expand The second messenger cGMP is a major intracellular mediator of the vaso-active agents nitric oxide and natriuretic peptides. The… Expand We isolated a constitutively active form of cGMP-dependent protein kinase Ialpha (cGK Ialpha) by PCR-driven random mutagenesis… Expand In mammalian tissues two types of cGMP-dependent protein kinase (cGK) have been identified. In contrast to the dimeric cGK I, cGK… Expand The apical membrane of intestinal epithelial cells harbors a unique isozyme of cGMP-dependent protein kinase (cGK type II) which… Expand A purified bovine lung cGMP-binding cGMP-specific phosphodiesterase (cG-BPDE) was rapidly phosphorylated by purified bovine lung… Expand