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Pentetic Acid

Known as: Acid, Diethylenetriamine Pentaacetic, DTPA, Pentetic Acid [Chemical/Ingredient] 
An edetate and a chelating agent used in preparing radiopharmaceuticals. Pentetic acid (DTPA) has strong affinity for iron but also shows affinities… 
National Institutes of Health

Related topics

Related topics

50 relations
10 ML ipilimumab 5 MG/ML Injection [Yervoy]10 ML nivolumab 10 MG/ML Injection [Opdivo]40 ML bezlotoxumab 25 MG/ML Injection [Zinplava]5 ML pentetate calcium trisodium 200 MG/ML Injection

Narrower (31)

111In-DTPA-human epidermal growth factor111In-bis-5-hydroxytryptamide-diethylenetriamine-pentaacetate111In-diDTPA-FKYK2-(4-aminobenzyl)diethylenetriaminepentaacetic acid

Broader (3)

Chelating AgentsIron Chelating AgentsPentetate

Papers overview

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Highly Cited
1994
Highly Cited
1994
Pinhole SPECT: an approach to in vivo high resolution SPECT imaging in small laboratory animals.
UNLABELLED The performance of pinhole SPECT and the application of this technology to investigate the localization properties of… 
Highly Cited
1994
Highly Cited
1994
Evaluation of the serum stability and in vivo biodistribution of CHX-DTPA and other ligands for yttrium labeling of monoclonal antibodies.
UNLABELLED Serum stability and in vivo biodistribution of both A and B isomers of the 2-(p-isothiocyanatobenzyl) (p-SCN-Bz… 
Highly Cited
1991
Highly Cited
1991
Oxidative glycation and free radical production: a causal mechanism of diabetic complications.
Glucose may oxidise under physiological conditions and lead to the production of protein reactive ketoaldehydes, hydrogen… 
Highly Cited
1990
Highly Cited
1990
Yttrium-90-labeled monoclonal antibody for therapy: labeling by a new macrocyclic bifunctional chelating agent.
Yttrium-90 (90Y) is a promising radiometal for therapy of cancer due to its high-energy beta emission and a physical half-life of… 
Highly Cited
1989
Highly Cited
1989
Nature of the bifunctional chelating agent used for radioimmunotherapy with yttrium-90 monoclonal antibodies: critical factors in determining in vivo survival and organ toxicity.
One factor that is critical to the potential effectiveness of radioimmunotherapy is the design of radiometal-chelated antibodies… 
Highly Cited
1987
Highly Cited
1987
Gadolinium-labeled liposomes: targeted MR contrast agents for the liver and spleen.
A contrast agent for use in magnetic resonance (MR) imaging of the liver and spleen has been designed in which gadolinium-DTPA is… 
Highly Cited
1985
Highly Cited
1985
Copper chelates as probes of biological systems: stable copper complexes with a macrocyclic bifunctional chelating agent.
Highly Cited
1984
Highly Cited
1984
Pulmonary epithelial permeability in hyaline-membrane disease.
Neonatal hyaline-membrane disease is complicated by pulmonary edema, yet left atrial pressures are normal. Alveolar-capillary… 
Highly Cited
1983
Highly Cited
1983
The preparation of DTPA-coupled antibodies radiolabeled with metallic radionuclides: an improved method.
Highly Cited
1972
Highly Cited
1972
Evaluation of 99mTc-DTPA for the Measurement of Glomerular Filtration Rate
Summary The usefulness of 99mTc-DTPA as an agent for measuring glomerular filtration rate was evaluated in five dogs and 11 human… 
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