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Transgenic mouse model of AA amyloidosis.
Evaluation of fluorine-18-BPA-fructose for boron neutron capture treatment planning.
Information on the pharmacokinetics of the 18F-labeled analog of BPA-Fr in two patients with glioblastoma multiforme was noninvasively obtained and distribution by PET was found to be consistent with tumor as identified by MR imaging.
Biodistribution and Subcellular Localization of an Unnatural Boron-Containing Amino Acid (Cis-ABCPC) by Imaging Secondary Ion Mass Spectrometry for Neutron Capture Therapy of Melanomas and Gliomas
The significant improvement in boron uptake by both the main tumor mass and infiltrating tumor cells compared to those reported in animal and clinical studies of p-boronophenylalanine strongly suggest that cis-ABCPC has the potential to become a novel new borons delivery agent for neutron capture therapy of gliomas and melanomas.
Communicating hydrocephalus in dogs with congenital ciliary dysfunction.
The ventricular dilation in CCD dogs is not due to impedance of CSF flow from the ventricular system by dysfunctional ependymal cilia, and suggests that the vents are not affected by impedance ofCSF flow by dysfunctionalEpendymAL cilia.
Synthesis and characterization of radioiodinated N-(3-iodopropen-1-yl)-2 beta-carbomethoxy-3 beta-(4-chlorophenyl)tropanes: potential dopamine reuptake site imaging agents.
- M. Goodman, M. Kung, G. Kabalka, H. Kung, R. Switzer
- Chemistry, BiologyJournal of medicinal chemistry
- 13 May 1994
These studies indicate that iodine-123-labeled E-13 is a potentially useful agent for imaging the dopamine reuptake sites by single-photon-emission computerized tomography.
Facile synthesis of N‐succinimidyl 4‐[18F]fluorobenzoate ([18F]SFB) for protein labeling
The purified [18F]SFB was used for the labeling of Avastin™ (Bevacizumab) through [ 18F]fluorobenzoylation of the AvastIn's α-amino groups.
High resolution computed tomography and MRI for monitoring lung tumor growth in mice undergoing radioimmunotherapy: correlation with histology.
It is concluded that the microCT method used could identify some lung tumors as small as 100 microm in diameter; however, no concrete evaluation of therapy induced regression of the tumors could be made with CT analyses alone.
In-target production of [13N]ammonia via proton irradiation of dilute aqueous ethanol and acetic acid mixtures.
Quantitative evaluation of boron neutron capture therapy (BNCT) drugs for boron delivery and retention at subcellular‐scale resolution in human glioblastoma cells with imaging secondary ion mass…
Cryogenically prepared cultured human T98G glioblastoma cells were evaluated for boron uptake and retention of two delivery agents and BPA, used clinically for BNCT, provided support for individualized treatment planning regimens rather than the use of fixed BPA infusion protocols.
Noninvasive High Field MRI Brain Imaging of the Garter Snake (Thamnophis sirtalis)
The value of noninvasive neural imaging in comparative and experimental studies of squamate reptiles will become increasingly recognized as the technology is further developed but can be effectively employed at present.