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Pempidine

Known as: Pempidine [Chemical/Ingredient], Piperidine, 1,2,2,6,6-pentamethyl- 
A nicotinic antagonist most commonly used as an experimental tool. It has been used as a ganglionic blocker in the treatment of hypertension but has… Expand
National Institutes of Health

Papers overview

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2006
2006
The concept of drug receptors has played a significant role in the biomedical sciences and in pharmaceutical innovation in the… Expand
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2006
2006
The modulation of [3H]ACh release by nicotinic compounds was studied in superfused rat hippocampal synaptosomes loaded with [3H… Expand
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Highly Cited
2000
Highly Cited
2000
The cinchona alkaloid-mediated opening of prochiral cyclic anhydrides in the presence of methanol leading to optically active… Expand
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Highly Cited
1990
Highly Cited
1990
Presynaptic nicotinic acetylcholine receptors on striatal nerve terminals modulate the release of dopamine. We have compared the… Expand
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1990
1990
The nature of mecamylamine's and pempidine's antagonism of nicotine in the central nervous system has not been defined clearly… Expand
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Review
1989
Review
1989
Revue bibliographique sur les recepteurs a nicotine existants au niveau du systeme nerveux central et en particulier etude de la… Expand
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1989
1989
The nicotinic agonists dimethylphenylpiperazinium iodide (DMPP) and carbachol (CARB) as well as (-)nicotine [-)NIC) were tested… Expand
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Highly Cited
1988
Highly Cited
1988
The nicotinic acetylcholine channel blockers mecamylamine (MECA) and pempidine (PEMP) blocked voltage-clamped isolated catfish… Expand
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Highly Cited
1984
Highly Cited
1984
The nicotinic cholinergic antagonist, dihydro-beta-erythroidine, binds to two sites in rat cortical membranes with dissociation… Expand
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Highly Cited
1979
Highly Cited
1979
Abstract Rat striatal slices were continuously superfused with 3H-tyrosine to study the effect of a low concentration of nicotine… Expand
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