Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Pempidine

Known as: Pempidine [Chemical/Ingredient], Piperidine, 1,2,2,6,6-pentamethyl- 
A nicotinic antagonist most commonly used as an experimental tool. It has been used as a ganglionic blocker in the treatment of hypertension but has… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1990
Highly Cited
1990
Abstract: Presynaptic nicotinic acetylcholine receptors on striatal nerve terminals modulate the release of dopamine. We have… Expand
1990
1990
The nature of mecamylamine's and pempidine's antagonism of nicotine in the central nervous system has not been defined clearly… Expand
Highly Cited
1988
Highly Cited
1988
The nicotinic acetylcholine channel blockers mecamylamine (MECA) and pempidine (PEMP) blocked voltage-clamped isolated catfish… Expand
Review
1982
Review
1982
  • G. Bammer
  • Neuroscience & Biobehavioral Reviews
  • 1982
  • Corpus ID: 20475634
The roles of acetylcholine (ACh), noradrenaline (NA), dopamine (DA) and serotonin (5-HT) in passive avoidance responding are… Expand
Highly Cited
1979
Highly Cited
1979
1. The production of corticotrophin releasing hormone (CRH) by the rat hypothalamus in vitro was studied in the presence and… Expand
Highly Cited
1979
Highly Cited
1979
Abstract Rat striatal slices were continuously superfused with 3H-tyrosine to study the effect of a low concentration of nicotine… Expand
Highly Cited
1977
Highly Cited
1977
The release of [3H] dopamine ([3H] DA) was estimated in serial superfusate fractions of rat striatal slices continuously… Expand
Highly Cited
1977
Highly Cited
1977
Rat striatal slices (two) were superfused continuously with L-3,5-3H tyrosine and 3H-dopamine (3H-DA) release was estimated in… Expand
Highly Cited
1974
Highly Cited
1974
1. The release of antidiuretic hormone (ADH) has been studied in the chloralose anaesthetized cat after microinjection of various… Expand
1973
1973
  • I. Hendry
  • Brain research
  • 1973
  • Corpus ID: 32417535
Abstract The response of the normal and surgically decentralized mouse superior cervical ganglion to nerve growth factor (NGF… Expand