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PYCARD wt Allele
Known as:
PYD and CARD Domain Containing wt Allele
, ASC
, MGC10332
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Human PYCARD wild-type allele is located within 16p12-p11.2 and is approximately 2 kb in length. This allele, which encodes apoptosis-associated…
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National Institutes of Health
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Related topics
Related topics
8 relations
16p12-p11.2
Apoptosis
Caspase Activation
Homo sapiens
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Broader (1)
PYCARD gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
ASC Induces Apoptosis via Activation of Caspase-9 by Enhancing Gap Junction-Mediated Intercellular Communication
M. Kitazawa
,
S. Hida
,
+8 authors
Shin-ichi Miyagawa
PLoS ONE
2017
Corpus ID: 18370794
ASC (apoptosis-associated speck-like protein containing a CARD) is a key adaptor molecule of inflammasomes that mediates…
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2012
2012
Polyacetylene Compound from Cirsium japonicum var. ussuriense Inhibited Caspase-1-mediated IL-1β Expression
H. Shim
,
J. Moon
,
S. Lee
,
Dongsool Yim
,
T. Kang
Immune Network
2012
Corpus ID: 15539961
Our previous report showed that polyacetylene compound, 1-Heptadecene-11, 13-diyne-8, 9, 10-triol (PA) from the root of Cirsium…
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2011
2011
Demethylation of TMS1 gene sensitizes thyroid cancer cells to TRAIL-induced apoptosis.
A. K. Siraj
,
A. Hussain
,
+6 authors
K. Al-Kuraya
Journal of Clinical Endocrinology and Metabolism
2011
Corpus ID: 23613252
CONTEXT TMS1 is a tumor suppressor gene that encodes for caspase recruitment domain containing regulatory protein and has been…
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2010
2010
Epigenetic alterations in disseminated neuroblastoma tumour cells: influence of TMS1 gene hypermethylation in relapse risk in NB patients
E. Grau
,
F. Martínez
,
+7 authors
V. Castel
Journal of Cancer Research and Clinical Oncology
2010
Corpus ID: 11082414
PurposeMost neuroblastoma patients over 18 months of age at diagnosis present disseminated disease. The presence of neuroblastoma…
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2010
2010
TMS, a chemically modified herbal derivative of Resveratrol, induces cell death by targeting Bax
S. Aiyar
,
Hoyong Park
,
+8 authors
R. Santen
Breast Cancer Research and Treatment
2010
Corpus ID: 2410845
Breast cancer recurrence after an initial favorable response to treatment is a major concern for patients who receive hormonal…
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2009
2009
Methylation-sensitive Regulation of TMS1/ASC by the Ets Factor, GA-binding Protein-α*
M. Lucas
,
Krista S. Crider
,
D. Powell
,
Priya Kapoor-Vazirani
,
P. Vertino
Journal of Biological Chemistry
2009
Corpus ID: 42428659
Epigenetic silencing involving the aberrant DNA methylation of promoter-associated CpG islands is one mechanism leading to the…
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2004
2004
Subcellular localisation of marenostrin/pyrin isoforms carrying the most common mutations involved in familial Mediterranean fever in the presence or absence of its binding partner ASC
C. Cazeneuve
,
S. Papin
,
I. Jéru
,
P. Duquesnoy
,
S. Amselem
Journal of Medical Genetics
2004
Corpus ID: 27002480
Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterised by recurrent episodes of fever and serosal…
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Highly Cited
2003
Highly Cited
2003
Caspy, a Zebrafish Caspase, Activated by ASC Oligomerization Is Required for Pharyngeal Arch Development*
J. Masumoto
,
Weibin Zhou
,
+10 authors
N. Inohara
Journal of Biological Chemistry
2003
Corpus ID: 35930066
The pyrin domain was identified recently in multiple proteins that are associated with apoptosis and/or inflammation, but the…
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2002
2002
A proapoptotic caspase recruitment domain protein gene, TMS1, is hypermethylated in human breast and gastric cancers.
R. Moriai
,
N. Tsuji
,
+4 authors
N. Watanabe
Anticancer Research
2002
Corpus ID: 21399185
BACKGROUND Conway et al. demonstrated that methylation of the proapoptotic gene, TMS1, was observed in breast cancer cell lines…
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1985
1985
Transcription of Agrobacterium rhizogenes A4 T-DNA
B. Taylor
,
F. White
,
E. Nester
,
M. Gordon
Molecular and General Genetics MGG
1985
Corpus ID: 27089434
SummaryTwo distinct segments of transferred DNA (T-DNA) were detected in tumor tissue incited by Agrobacterium rhizogenes strain…
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