PYCARD gene

Known as: CARD5, PYD and CARD domain containing, TARGET OF METHYLATION-INDUCED SILENCING 1 
This gene plays a role in the regulation of apoptosis.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Administration of mesenchymal stem cells (MSCs) represents a promising treatment option for patients suffering from immunological… (More)
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Highly Cited
2011
Highly Cited
2011
The emergence of chronic inflammation during obesity in the absence of overt infection or well-defined autoimmune processes is a… (More)
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Highly Cited
2010
Highly Cited
2010
Colitis-associated cancer (CAC) is a major complication of inflammatory bowel diseases. We show that components of the… (More)
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Highly Cited
2010
Highly Cited
2010
The NLR gene family mediates host immunity to various acute pathogenic stimuli, but its role in chronic infection is not known… (More)
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Highly Cited
2009
Highly Cited
2009
The nucleotide-binding domain and leucine-rich-repeat-containing (NLR) family of pattern-recognition molecules mediate host… (More)
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Highly Cited
2008
Highly Cited
2008
Aluminium adjuvants, typically referred to as ‘alum’, are the most commonly used adjuvants in human and animal vaccines worldwide… (More)
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Highly Cited
2006
Highly Cited
2006
Mutations in cryopyrin and pyrin proteins are responsible for several autoinflammatory disorders in humans, suggesting that these… (More)
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Highly Cited
2004
Highly Cited
2004
Specific adaptors regulate the activation of initiator caspases; for example, FADD and Apaf-1 engage caspases 8 and 9… (More)
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Highly Cited
2004
Highly Cited
2004
Several autoinflammatory disorders are associated with missense mutations within the nucleotide-binding oligomerization domain of… (More)
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Highly Cited
2002
Highly Cited
2002
Generation of Interleukin (IL)-1beta via cleavage of its proform requires the activity of caspase-1 (and caspase-11 in mice), but… (More)
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