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PX-12
Known as:
1-methylpropyl 2-imidazolyl disulfide
, Thioredoxin-1 Inhibitor PX-12
An orally bioavailable small molecule with potential antineoplastic activity. Thioredoxin-1 inhibitor PX-12 irreversibly binds to thioredoxin-1 (Trx…
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National Institutes of Health
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Related topics
Related topics
2 relations
IV 2 compound
NCIt Antineoplastic Agent Terminology
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
The role of thioredoxin and T-type Ca2+ channels in vascular smooth muscle cell proliferation
Emily Johnson
2016
Corpus ID: 89627041
Elevated vascular smooth muscle cell (VSMC) proliferation is a feature of various cardiovascular conditions including restenosis…
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2011
2011
Thioredoxin-1 ist vermindert in aktiver Colitis Crohn und aktiver Colitis ulcerosa und moduliert die angeborene antimikrobielle Abwehr
S. Jäger
,
B. Schröder
,
Julia Beisner
,
M. Gersemann
,
E. Stange
,
J. Wehkamp
2011
Corpus ID: 75292091
2006
2006
NovelThioredoxin Inhibitors Paradoxically Increase Hypoxia-Inducible Factor-A Expression but Decrease Functional Transcriptional Activity , DNABinding , and Degradation
Dylan T. Jones
,
C. Pugh
,
S. Wigfield
,
M. Stevens
,
A. Harris
2006
Corpus ID: 3017463
Purpose:Hypoxia-inducible factor-a (HIF-a) is a transcription factor that regulates the response to hypoxia. HIF-a protein is…
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2005
2005
SURFACE-ENHANCED LASER DESORPTION/IONIZATION TIME-OF-FLIGHT MASS SPECTROSCOPY (SELDI-TOF-MS) AS A TOOL FOR MOLECULAR ENDPOINT ANALYSIS OF PX-12, A THIOREDOXIN-1 INHIBITOR
W. Tate
2005
Corpus ID: 93812119