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PVRL1 protein, human

Known as: Poliovirus Receptor-Related 1, Herpesvirus Ig-Like Receptor, Poliovirus Receptor-Like 1 
Nectin-1 (517 aa, ~57 kDa) is encoded by the human PVRL1 gene. This protein plays a role in both the formation of cell-cell contact points and host… 
National Institutes of Health

Related topics

Related topics

16 relations
Cell AdhesionCell-Cell Adhesion ProcessClusters of differentiationImmunoglobulin C2-set Domain

Broader (2)

nectin-1nectins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Invasion of Herpes Simplex Virus 1 into Murine Dermis: Role of Nectin-1 and Herpesvirus Entry Mediator as Cellular Receptors during Aging
HSV-1 is a prevalent human pathogen which invades skin and mucocutaneous linings. So far, the underlying mechanisms of how the… 
2014
2014
Epithelial-mesenchymal transition enhances response to oncolytic herpesviral therapy through nectin-1.
Cancers exhibiting epithelial-mesenchymal transition (EMT) are associated with aggressive behavior and increased metastatic… 
2012
2012
Nectins localize Willin to cell–cell junctions
Willin is a FERM‐domain protein, which is related to the Drosophila Expanded, a protein known to be a component of the Hippo… 
2009
2009
Fusion protein consisting of the first immunoglobulin‐like domain of porcine nectin‐1 and Fc portion of human IgG1 provides a marked resistance against pseudorabies virus infection to transgenic mice
Nectin‐1 is a Ca2+‐independent Ig‐like cell–cell adhesion molecule and an alphaherpesvirus receptor that binds to virion… 
2008
2008
The host adherens junction molecule nectin-1 is downregulated in Chlamydia trachomatis-infected genital epithelial cells.
Nectin-1, a member of the immunoglobulin superfamily, is a Ca(2+)-independent cell adhesion protein implicated in the… 
2007
2007
Involvement of integrin‐induced activation of protein kinase C in the formation of adherens junctions
In epithelial cells, tight junctions (TJs) and adherens junctions (AJs) form junctional complexes. At AJs, cadherins and nectins… 
2006
2006
The first immunoglobulin-like domain of porcine nectin-1 is sufficient to confer resistance to pseudorabies virus infection in transgenic mice
Summary.Nectin-1 is an alphaherpesvirus receptor that binds to virion glycoprotein D (gD). Porcine nectin-1 mediates entry of… 
2005
2005
Deletion of the Second Immunoglobulin-Like Domain of Nectin-1 Alters Its Intracellular Processing and Localization and Ability To Mediate Entry of Herpes Simplex Virus
ABSTRACT Nectin-1 is an immunoglobulin (Ig)-like entry receptor for herpes simplex virus (HSV). Like other nectins, nectin-1… 
2004
2004
Effects of linker-insertion mutations in herpes simplex virus 1 gD on glycoprotein-induced fusion with cells expressing HVEM or nectin-1.
Highly Cited
2003
Highly Cited
2003
Cellular Localization of Nectin-1 and Glycoprotein D during Herpes Simplex Virus Infection
ABSTRACT During viral entry, herpes simplex virus (HSV) glycoprotein D (gD) interacts with a specific cellular receptor such as… 
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