Skip to search formSkip to main contentSkip to account menu

PVRL1 protein, human

Known as: Poliovirus Receptor-Related 1, Herpesvirus Ig-Like Receptor, Poliovirus Receptor-Like 1 
Nectin-1 (517 aa, ~57 kDa) is encoded by the human PVRL1 gene. This protein plays a role in both the formation of cell-cell contact points and host… 
National Institutes of Health

Related topics

Related topics

16 relations
Cell AdhesionCell-Cell Adhesion ProcessClusters of differentiationImmunoglobulin C2-set Domain

Broader (2)

nectin-1nectins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Structure of Herpes Simplex Virus Glycoprotein D Bound to the Human Receptor Nectin-1
Binding of herpes simplex virus (HSV) glycoprotein D (gD) to a cell surface receptor is required to trigger membrane fusion… 
Highly Cited
2008
Highly Cited
2008
HVEM and nectin-1 are the major mediators of herpes simplex virus 1 (HSV-1) entry into human conjunctival epithelium.
PURPOSE The human conjunctiva is a natural target for herpes simplex virus (HSV)-1 infection. The goals of this study were to… 
Highly Cited
2007
Highly Cited
2007
Alternative entry receptors for herpes simplex virus and their roles in disease.
Highly Cited
2007
Highly Cited
2007
Cooperative roles of Par-3 and afadin in the formation of adherens and tight junctions
Par-3 is a cell-polarity protein that regulates the formation of tight junctions (TJs) in epithelial cells, where claudin is a… 
Highly Cited
2005
Highly Cited
2005
Roles of cell-adhesion molecules nectin 1 and nectin 3 in ciliary body development
Nectins are Ca2+-independent immunoglobulin-like cell-cell-adhesion molecules consisting of four members. Nectins homophilically… 
Highly Cited
2004
Highly Cited
2004
In Vivo Role of Nectin-1 in Entry of Herpes Simplex Virus Type 1 (HSV-1) and HSV-2 through the Vaginal Mucosa
ABSTRACT Herpes simplex virus type 2 (HSV-2) is transmitted through the genital mucosa during sexual encounters. In recent years… 
Highly Cited
2004
Highly Cited
2004
Comparative usage of herpesvirus entry mediator A and nectin-1 by laboratory strains and clinical isolates of herpes simplex virus.
Highly Cited
2003
Highly Cited
2003
Direct Binding of Cell Polarity Protein PAR-3 to Cell-Cell Adhesion Molecule Nectin at Neuroepithelial Cells of Developing Mouse*
PAR-3 is a cell polarity protein that localizes at tight junctions (TJs) by direct binding to an immunoglobulin (Ig)-like cell… 
Highly Cited
2000
Highly Cited
2000
Nectin-3, a New Member of Immunoglobulin-like Cell Adhesion Molecules That Shows Homophilic and Heterophilic Cell-Cell Adhesion Activities*
We have isolated a novel cell-cell adhesion system localized at cadherin-based adherens junctions (AJs). This system consists of… 
Highly Cited
1998
Highly Cited
1998
Herpes Simplex Virus Glycoprotein D Can Bind to Poliovirus Receptor-Related Protein 1 or Herpesvirus Entry Mediator, Two Structurally Unrelated Mediators of Virus Entry
ABSTRACT Several cell membrane proteins have been identified as herpes simplex virus (HSV) entry mediators (Hve). HveA (formerly… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)