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PTTG1 wt Allele

Known as: Pituitary Tumor-Transforming 1 wt Allele, TUTR1, hPTTG 
Human PTTG1 wild-type allele is located in the vicinity of 5q35.1 and is approximately 7 kb in length. This allele, which encodes securing protein… Expand
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
BACKGROUND The pituitary tumour transforming gene (pttg) plays a central role in pituitary tumorigenesis, but PTTG protein… Expand
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Highly Cited
2004
Highly Cited
2004
The proto-oncogene pituitary tumor-transforming gene (PTTG) is described as abundantly overexpressed in a variety of neoplasms… Expand
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Highly Cited
2003
Highly Cited
2003
OBJECTIVE Pituitary tumour transforming gene (PTTG) encodes a multifunctional protein that is implicated in initiating and… Expand
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Highly Cited
2003
Highly Cited
2003
Differentiated thyroid cancers are the most common endocrine cancers, but there are no reliable molecular markers of prognosis… Expand
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Highly Cited
2002
Highly Cited
2002
Pituitary tumorigenesis is a poorly understood process involving dysregulation of the cell cycle, proliferation, and angiogenesis… Expand
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Highly Cited
2002
Highly Cited
2002
Pituitary hyperplasia and lactotroph replication are induced by estrogen. The product of the pituitary tumor transforming gene… Expand
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Highly Cited
2001
Highly Cited
2001
Tumorigenic pituitary tumor transforming gene (PTTG) is a mammalian homolog of Xenopus securin that inhibits chromatid separation… Expand
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Highly Cited
1999
Highly Cited
1999
We recently cloned a novel pituitary tumor transforming gene (PTTG). Here we report PTTG expression in human pituitary adenomas… Expand
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Highly Cited
1999
Highly Cited
1999
Despite advances in characterizing the pathophysiology and genetics of pituitary tumors, molecular mechanisms of their… Expand
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Highly Cited
1999
Highly Cited
1999
Pituitary tumors are commonly encountered, and result from clonal expansion of a single mutated cell. Hypothalamic hormones… Expand
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