• Publications
  • Influence
Clinical practice guidelines for multiple endocrine neoplasia type 1 (MEN1).
OBJECTIVE The aim was to provide guidelines for evaluation, treatment, and genetic testing for multiple endocrine neoplasia type 1 (MEN1). PARTICIPANTS The group, which comprised 10 experts,Expand
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Diagnosis and treatment of hyperprolactinemia: an Endocrine Society clinical practice guideline.
OBJECTIVE The aim was to formulate practice guidelines for the diagnosis and treatment of hyperprolactinemia. PARTICIPANTS The Task Force consisted of Endocrine Society-appointed experts, aExpand
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Acromegaly: an endocrine society clinical practice guideline.
OBJECTIVE The aim was to formulate clinical practice guidelines for acromegaly. PARTICIPANTS The Task Force included a chair selected by the Endocrine Society Clinical Guidelines SubcommitteeExpand
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Criteria for cure of acromegaly: a consensus statement.
In February 1999, a workshop was held in Cortina, Italy to develop a consensus defining the criteria for cure of acromegaly. The workshop was sponsored by the University of Brescia and hosted by theExpand
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Medical progress: Acromegaly.
  • S. Melmed
  • Medicine
  • The New England journal of medicine
  • 14 December 2006
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Guidelines for acromegaly management: an update.
OBJECTIVE The Acromegaly Consensus Group reconvened in November 2007 to update guidelines for acromegaly management. PARTICIPANTS The meeting participants comprised 68 pituitary specialists,Expand
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A consensus on criteria for cure of acromegaly.
OBJECTIVE The Acromegaly Consensus Group met in April 2009 to revisit the guidelines on criteria for cure as defined in 2000. PARTICIPANTS Participants included 74 neurosurgeons andExpand
  • 580
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Structure, expression, and function of human pituitary tumor-transforming gene (PTTG).
Despite advances in characterizing the pathophysiology and genetics of pituitary tumors, molecular mechanisms of their pathogenesis are poorly understood. Recently, we isolated a transforming geneExpand
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Acromegaly pathogenesis and treatment.
  • S. Melmed
  • Medicine
  • The Journal of clinical investigation
  • 2 November 2009
Dysregulated growth hormone (GH) hypersecretion is usually caused by a GH-secreting pituitary adenoma and leads to acromegaly - a disorder of disproportionate skeletal, tissue, and organ growth. HighExpand
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Isolation and characterization of a pituitary tumor-transforming gene (PTTG).
Pathogenesis of tumor formation in the anterior pituitary has been intensively studied, but the common mechanism involved in pituitary cell transformation and tumorigenesis remains elusive. In thisExpand
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