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PTPN22 gene

Known as: PROTEIN-TYROSINE PHOSPHATASE, NONRECEPTOR-TYPE 8, FORMERLY, PTPN22, LYP 
This gene plays a role in the regulation of the immune system, the development of autoimmunity and the cellular response to pathogens.
National Institutes of Health

Related topics

Related topics

15 relations
Cell Differentiation processCell ProliferationDephosphorylationDiabetes Mellitus, Insulin-Dependent

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PTPN22 wt Allele

Papers overview

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2018
2018
Frequency of human leukocyte antigens class II-DR alleles (HLA-DRB1) in Argentinian patients with early arthritis
Patients with rheumatoid arthritis (RA) or undifferentiated arthritis (UA) in the CONAART database (Argentine Consortium for… 
2017
2017
The PTPN22 R263Q polymorphism confers protection against systemic lupus erythematosus and rheumatoid arthritis, while PTPN22 R620W confers susceptibility to Graves’ disease in a Mexican population
The functional PTPN22 R620W polymorphism (rs2476601) is clearly associated with susceptibility to several autoimmune diseases… 
2015
2015
Density functional theory (B3LYP/6-311+G**) study of some semicarbazones formation mechanism
Mechanism of formations of (E)-2-(1-phenylethylidene)hydrazinecarboxamide, 2cyclohexyldenehydrazinecarboxamide, (Z)-2-(1… 
2015
2015
Evaluation of ethanol production from potato, cassava and orange wastage in discontinuos cultivation using Saccharomyces cerevisiae
The present research aimed to produce ethanol using glucose syrup made from potato, orange and cassava wastage, using… 
2012
2012
ERK 1 / 2 MAPKs and Wnt Signaling Pathways are Independently Involved in Adipocytokine-Mediated Aldosterone
▼ Obesity is one major risk factor for the development of arterial hypertension, and the development of obesity-related… 
2011
2011
Genetik bei Kollagenosen
  • Dr. I. Melchers
  • Zeitschrift für Rheumatologie (Print)
  • 2011
  • Corpus ID: 20306137
ZusammenfassungGenetische Risikofaktoren gibt es bei allen Kollagenosen. Am wichtigsten sind sie beim systemischen Lupus… 
2008
2008
Study on the relationship between polymorphism of PTPN22 and Graves'disease of Han nationality in Chongqing area
Objective:To investigate the relationship between the polymorphism of PTPN22 gene exon14 C1858T and Graves' disease(GD)in Han… 
2007
2007
B 3 LYP density functional calculations on the ground-state structure , elastic properties , and compression mechanism of-ZrW 2 O 8
The structure of -ZrW2O8 was optimized at different pressures and its elastic constants were calculated at the B3LYP density… 
2000
2000
No association to type 1 diabetes of the human homologue of rat Lyp in the Danish population
1986
1986
Identification of two distinct regions within the binding sites for fibrinogen and fibronectin on the IIb-IIIa human platelet membrane glycoprotein complex by monoclonal antibodies P2 and P4.
The effect of two monoclonal antibodies P2 (LyP 2) or P4 (LyP 4), specific for the platelet membrane glycoprotein IIb/IIIa…