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PTPN22 wt Allele

Known as: LYP, Lyp2, Lyp1 
Human PTPN22 wild-type allele is located within 1p13.3-p13.1 and is approximately 123 kb in length. This allele, which encodes tyrosine-protein… Expand
National Institutes of Health

Related topics

Related topics

14 relations
1p13.3-p13.1Cell Differentiation processCell ProliferationDephosphorylation
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Broader (1)

PTPN22 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Extracellular loops matter – subcellular location and function of the lysine transporter Lyp1 from Saccharomyces cerevisiae
Yeast amino acid transporters of the APC superfamily are responsible for the proton motive force‐driven uptake of amino acids… Expand
2020
2020
Membrane Lipid Requirements of the Lysine Transporter Lyp1 from Saccharomyces cerevisiae.
Membrane lipids act as solvents and functional cofactors for integral membrane proteins. The yeast plasma membrane is unusual in… Expand
Highly Cited
2016
Highly Cited
2016
Asymmetry in inward- and outward-affinity constant of transport explain unidirectional lysine flux in Saccharomyces cerevisiae
The import of basic amino acids in Saccharomyces cerevisiae has been reported to be unidirectional, which is not typical of how… Expand
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2016
2016
Directed evolution to decipher lysine-proton coupling in the yeast amino acid transporter Lyp1
In proton-coupled secondary transporters, conserved anionic residues situated in transmembrane helices often play a role in… Expand
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2014
2014
Converting the Yeast Arginine Can1 Permease to a Lysine Permease*
Background: Can1 is a yeast plasma membrane permease catalyzing specific uptake of arginine. Results: Two residues in the binding… Expand
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2011
2011
Synthesis and activity evaluation of a new bestatin derivative LYP2 as an aminopeptidase N inhibitor
As a ubiquitous enzyme overexpressed on the epithelium of the tumor, aminopeptidase N (APN) plays important roles in the… Expand
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