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PTK2 wt Allele

Known as: FADK, FAK, FAK1 
Human PTK2 wild-type allele is located within 8q24-qter and is approximately 343 kb in length. This allele, which encodes focal adhesion kinase 1… 
National Institutes of Health

Related topics

Related topics

26 relations
8q24-qterAgrin PathwayAngiogenesis PathwayAngiotensin II Signaling Pathway

Broader (1)

PTK2 gene

Papers overview

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2001
2001
Localized activation of m‐calpain in migrating human umbilical vein endothelial cells stimulated by shear stress
Using a parallel‐plate flow‐chamber and confocal laser scanning microscopy (CLSM), we studied the mode of cytoskeletal… 
1998
1998
Full-spreading platelets induced by the recombinant rhodostomin are via binding to integrins and correlated with FAK phosphorylation.
1997
1997
The integrin-triggered rescue of T lymphocyte apoptosis is blocked in HIV-1-infected individuals.
HIV infection is associated with a disease status-dependent impairment of Ag-specific T cell responses, resulting in anergy or… 
Review
1996
Review
1996
pp125FAK in the focal adhesion.
Highly Cited
1995
Highly Cited
1995
T cell receptor- and beta 1 integrin-mediated signals synergize to induce tyrosine phosphorylation of focal adhesion kinase (pp125FAK) in human T cells
The beta 1 subfamily of integrins is thought to play an important role in both the adhesion/migration and proliferation… 
1995
1995
Characterization of adhesion plates induced by the interaction of Entamoeba histolytica trophozoites with fibronectin.
Entamoeba histolytica trophozoites are pleiomorphic and highly motile cells. Although scarce fibrous material can be identified… 
1995
1995
Regulation of lysophosphatidic acid-stimulated tyrosine phosphorylation of mitogen-activated protein kinase by protein kinase C- and pertussis toxin-dependent pathways in the endothelial cell line…
In the endothelial cell line EAhy 926, 1-oleoyl-lysophosphatidic acid (LPA) stimulated the tyrosine phosphorylation of the pp42… 
1995
1995
pp125FAK tyrosine kinase activity is not required for the assembly of F-actin stress fibres and focal adhesions in cultured mouse aortic smooth muscle cells.
The observed increase in phosphotyrosine content of focal adhesion-associated proteins, in response to integrin engagement… 
1994
1994
Lymphocyte antigen receptor activation of a focal adhesion kinase-related tyrosine kinase substrate.
One of the earliest responses of T and B lymphocytes to stimulation through their antigen receptors is the activation of protein… 
1994
1994
Regulation of adhesion-related protein tyrosine kinases during in vitro differentiation of retinal pigment epithelial cells: translocation of pp60c-src to the nucleus is accompanied by downregulation…
In the present report we show that induction of expression of a differentiated phenotype in cultured retinal pigmented epithelium… 
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