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PTK2 gene

Known as: PTK2 Protein Tyrosine Kinase 2 Gene, FAK1, FADK 
This gene plays a role in apoptosis, cell motility and proliferation.
National Institutes of Health

Related topics

Related topics

13 relations
ApoptosisCell Differentiation processCell ProliferationFAK activity

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PTK2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Structural pliability adjacent to the kinase domain highlights contribution of FAK1 IDRs to cytoskeletal remodeling.
2016
2016
Inhibition of FAK Exerts Anti-Leukemic Activity and Potentiates ABT-199-Induced Apoptosis in AML
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that regulates cell adhesion, proliferation, stem cell functions… 
2014
2014
Abstract 1610: MAPK inhibitor resistance leads to ligand-independent Ephrin A2 receptor signaling and the formation of new melanoma metastases
Melanoma is the deadliest form of skin cancer with the worst prognosis in patients with metastasis to distant sites such as brain… 
2013
2013
Integrative analysis of copy number alteration and gene expression profiling in ovarian clear cell adenocarcinoma.
2011
2011
Effect of FAK expression level on the motility, proliferation and apoptosis of SMMC—7721 cells
The siRNAs targeting FAK were designed and transfected into SMMC—7721 cells using a calcium phosphate transfection method.The… 
2009
2009
Identification of new target molecules PTK2, TGFBR2 and CD9 overexpressed during advanced bone marrow remodelling in primary myelofibrosis
Primary myelofibrosis (PMF) is a myeloproliferative neoplasm characterized by remodelling of the bone marrow, including… 
2009
2009
[Effects of FAK expression level on proliferation and motility of colorectal carcinoma cells].
AIM To investigate the effect of siRNA targeting FAK gene on proliferation and motility of colorectal cancer. METHODS… 
2004
2004
Down-regulation of procaspase-8 expression by focal adhesion kinase protects HL-60 cells from TRAIL-induced apoptosis.
2002
2002
Deletions of SKY1 or PTK2 in the Saccharomyces cerevisiae trk1Deltatrk2Delta mutant cells exert dual effect on ion homeostasis.
Sky1p and Ptk2p are protein kinases that regulate ion transport across the plasma membrane of Saccharomyces cerevisiae. We show… 
1983
1983
Analysis in Cos-1 cells of processing and polyadenylation signals by using derivatives of the herpes simplex virus type 1 thymidine kinase gene
Bal31 nuclease was used to resect the herpes simplex virus type 1 thymidine kinase (tk) gene from its 3' end, and a plasmid… 
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