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PSMD10 gene

Known as: Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 Gene, PSMD10, p28(GANK) 
This gene is involved in protein degradation.
National Institutes of Health

Related topics

Related topics

6 relations
ApoptosisIL27 genePSMD10 protein, humanPolyubiquitination

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The oncoprotein gankyrin promotes the development of colitis-associated cancer through activation of STAT3
Although long-standing colonic inflammation due to refractory inflammatory bowel disease (IBD) promotes the development of… 
Review
2016
Review
2016
Gankyrin regulates cell signaling network
Gankyrin is an oncoprotein that facilitates the degradation of two key tumor suppressors, namely, Rb and p53. Although Gankyrin… 
2016
2016
Gankyrin activates mTORC1 signaling by accelerating TSC2 degradation in colorectal cancer.
2013
2013
Association of Gankyrin and Stemness Factor Expression in Human Colorectal Cancer
BackgroundIt is widely accepted that the adenoma-carcinoma sequence represents the process by which most colorectal cancers (CRCs… 
Highly Cited
2010
Highly Cited
2010
Overexpression of a novel gene gankyrin correlates with the malignant phenotype of colorectal cancer
Gankyrin, a small and highly conserved protein which is identical to the p28 gene product, was found to be related with the… 
2009
2009
The overexpression of multidrug resistance-associated proteins and gankyrin contribute to arsenic trioxide resistance in liver and gastric cancer cells.
Arsenic trioxide has been used as a therapeutic agent for acute promyelocytic leukemia and recently for some solid tumors… 
2008
2008
Retinoblastoma protein modulates gankyrin–MDM2 in regulation of p53 stability and chemosensitivity in cancer cells
MDM2 is a key ubiquitin E3 ligase for p53 and its activity is critically regulated by a set of modulators, including ARF, p300… 
Highly Cited
2007
Highly Cited
2007
Structural basis for the recognition between the regulatory particles Nas6 and Rpt3 of the yeast 26S proteasome.
2007
2007
Evidence that Proteasome-Dependent Degradation of the Retinoblastoma Protein in Cells Lacking A-Type Lamins Occurs Independently of Gankyrin and MDM2
Background A-type lamins, predominantly lamins A and C, are nuclear intermediate filaments believed to act as scaffolds for… 
Highly Cited
2001
Highly Cited
2001
Sequential changes in hepatocarcinogenesis induced by diethylnitrosamine plus thioacetamide in Fischer 344 rats: Induction of gankyrin expression in liver fibrosis, pRB degradation in cirrhosis, and…
To clarify the sequential changes in pRB and p16 during different stages of hepatocarcinogenesis such as fibrosis, cirrhosis… 
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