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PSMA ADC

Known as: Prostate-specific Membrane Antigen Antibody-Drug Conjugate, Anti-PSMA Monoclonal Antibody-Monomethylauristatin E Conjugate, Anti-PSMA Monoclonal Antibody-MMAE Conjugate 
An antibody-drug conjugate (ADC) containing a fully human monoclonal antibody directed against prostate-specific membrane antigen (PSMA), conjugated… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Monoclonal Antibodies
NCIt Antineoplastic Agent Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Randomized prospective phase 3 trial of 68Ga-PSMA-11 PET/CT molecular imaging for prostate cancer salvage radiotherapy planning [PSMA-SRT].
TPS5101 Background: Salvage radiotherapy (SRT) for prostate cancer (PCa) recurrence after prostatectomy offers long-term… 
Review
2018
Review
2018
Novel technology of molecular radio-guidance for lymph node dissection in recurrent prostate cancer by PSMA-ligands
PurposeRecently, prostate-specific membrane antigen-radioguided surgery (PSMA-RGS) has been introduced as a promising new and… 
2017
2017
Gallium-68 or Fluorine-18 for prostate cancer imaging?
The introduction of prostate specific membrane antigen (PSMA)-positron emission tomography (PET) using 68Ga revolutionized… 
2017
2017
Comparison of PSMA-HBED and PSMA-I&T as diagnostic agents in prostate carcinoma
PurposeGallium(68)-labelled prostate-specific membrane antigen (PSMA) radiopharmaceuticals can be used to detect prostate cancer… 
2017
2017
Uptake of PSMA-ligands in normal tissues is dependent on tumor load in patients with prostate cancer
Radioligand therapy (RLT) with Lu-177-labeled PSMA-ligands is a new therapy option for prostate cancer. Biodistribution in normal… 
2017
2017
Radiochemistry and Preclinical PET Imaging of 68Ga-Desferrioxamine Radiotracers Targeting Prostate-Specific Membrane Antigen
Radiotracers incorporating the urea-based Glu-NH-C(O)-NH-Lys group have gained prominence due to their role in targeting prostate… 
2017
2017
Abstract 5200: Preclinical pharmacology of the PSMA-targeted thorium-227 conjugate PSMA-TTC: a novel targeted alpha therapeutic for the treatment of prostate cancer
Prostate-specific membrane antigen (PSMA, FOLH1) is a type II transmembrane glycoprotein of the M28 peptidase family that acts as… 
2015
2015
Sensitive ELISA Method for the Measurement of Catabolites of Antibody-Drug Conjugates (ADCs) in Target Cancer Cells.
A new, sensitive ELISA method has been developed which measures catabolites in cells and media upon processing of antibody-drug… 
Highly Cited
2014
Highly Cited
2014
Facile synthesis of PSMA-g-3ABA/MWCNTs nanocomposite as a substrate for hemoglobin immobilization: application to catalysis of H(2)O(2).
Highly Cited
2004
Highly Cited
2004
Anti‐tumor effects and lack of side effects in mice of an immunotoxin directed against human and mouse prostate‐specific membrane antigen
Prostate‐specific membrane antigen (PSMA) is a transmembrane protein that is largely restricted to prostatic epithelial cells in… 
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