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PSMA ADC

Known as: Prostate-specific Membrane Antigen Antibody-Drug Conjugate, Anti-PSMA Monoclonal Antibody-Monomethylauristatin E Conjugate, Anti-PSMA Monoclonal Antibody-MMAE Conjugate 
An antibody-drug conjugate (ADC) containing a fully human monoclonal antibody directed against prostate-specific membrane antigen (PSMA), conjugated… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Monoclonal Antibodies
NCIt Antineoplastic Agent Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
68Ga-PSMA-11 PET/CT derived quantitative volumetric tumor parameters for classification and evaluation of therapeutic response of bone metastases in prostate cancer patients
To evaluate the role of 68Gallium prostate-specific membrane antigen-positron emission tomography/computed tomography (68Ga-PSMA… 
Highly Cited
2017
Highly Cited
2017
Initial Experience with Volumetric 68Ga-PSMA I&T PET/CT for Assessment of Whole-Body Tumor Burden as a Quantitative Imaging Biomarker in Patients with Prostate Cancer
A quantitative imaging biomarker is desirable to provide a comprehensive measure of whole-body tumor burden in patients with… 
Highly Cited
2016
Highly Cited
2016
Pilot study: use of gallium-68 PSMA PET for detection of metastatic lesions in patients with renal tumour
BackgroundIn this study, we prospectively evaluate the diagnostic potential of a gallium-68 (68Ga) prostate-specific membrane… 
Highly Cited
2014
Highly Cited
2014
RNA aptamer-conjugated liposome as an efficient anticancer drug delivery vehicle targeting cancer cells in vivo.
Highly Cited
2013
Highly Cited
2013
A phase I dose escalation trial of vaccine replicon particles (VRP) expressing prostate-specific membrane antigen (PSMA) in subjects with prostate cancer.
Review
2013
Review
2013
Antibody-drug conjugate (ADC) clinical pipeline: a review.
Biological therapies play an increasing role in cancer treatment, although the number of naked antibodies showing clinical… 
Highly Cited
2011
Highly Cited
2011
In Vitro and In Vivo Responses of Advanced Prostate Tumors to PSMA ADC, an Auristatin-Conjugated Antibody to Prostate-Specific Membrane Antigen
Prostate-specific membrane antigen (PSMA) is a membrane protein that is overexpressed manifold in prostate cancer and provides an… 
Review
2011
Review
2011
Prostate-specific membrane antigen as a potential novel vascular target for treatment of glioblastoma multiforme.
CONTEXT Prostate-specific membrane antigen (PSMA) is expressed in endothelium of vessels in malignant solid tumors but not in… 
Highly Cited
2008
Highly Cited
2008
Synthesis and evaluation of technetium-99m- and rhenium-labeled inhibitors of the prostate-specific membrane antigen (PSMA).
The prostate-specific membrane antigen (PSMA) is increasingly recognized as a viable target for imaging and therapy of cancer. We… 
Highly Cited
2006
Highly Cited
2006
pH-responsive poly(styrene-alt-maleic anhydride) alkylamide copolymers for intracellular drug delivery.
Many macromolecular therapeutics such as peptides, proteins, antisense oligodeoxynucleotides (ASODN), and short interfering RNA… 
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