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PRPF4 gene

Known as: PRECURSOR mRNA-PROCESSING FACTOR 4, S. CEREVISIAE, HOMOLOG OF, HPRP4P, U4/U6 small nuclear ribonucleoprotein Prp4 
National Institutes of Health

Papers overview

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2019
2019
Background Hepatocellular carcinoma (HCC) is the second leading cause of death among cancers worldwide. In this study, we aimed… 
2014
2014
Pre-mRNA splicing by the spliceosome is an essential step in the maturation of nearly all human mRNAs. Mutations in six… 
2012
2012
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL We recently constructed a large-scale gene… 
Highly Cited
2002
Highly Cited
2002
We report that the cyclophilin USA‐CyP is part of distinct complexes with two spliceosomal proteins and is involved in both steps… 
2002
2002
Human splicing factors Hprp3p and Hprp4p are associated with the U4/U6 small nuclear ribonucleoprotein particle, which is… 
2001
2001
We provide evidence that Prp4p kinase activity is required for pre‐mRNA splicing in vivo and show that loss of activity impairs… 
2000
2000
Mitogen-activated protein kinases (MAPKs) and cyclin-dependent kinases (CDKs) are important proline-directed Ser/Thr kinases that… 
Highly Cited
1997
Highly Cited
1997
Immunoaffinity-purified human 25S [U4/U6.U5] tri-snRNPs harbor a set of polypeptides, termed the tri-snRNP proteins, that are not… 
1997
1997
Nuclear RNA splicing occurs in an RNA-protein complex, termed the spliceosome. U4/U6 snRNP is one of four essential small nuclear… 
1991
1991
SummaryWe have generated a bank of temperature-sensitive (ts) Schizosaccharomyces pombe mutant strains. About 150 of these…