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PRPF18 gene

Known as: hPrp18, pre-mRNA processing factor 18, PRPF18 
 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
The assembly of the spliceosome involves dynamic rearrangements of interactions between snRNAs, protein components, and the pre… Expand
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Highly Cited
2009
Highly Cited
2009
The spliceosome is a ribonucleoprotein machine that removes introns from pre-mRNA in a two-step reaction. To investigate the… Expand
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2007
2007
After the second transesterification step of pre-mRNA splicing, the Prp22 helicase catalyzes release of spliced mRNA by… Expand
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Highly Cited
2002
Highly Cited
2002
Slu7 and Prp18 act in concert during the second step of yeast pre-mRNA splicing. Here we show that the 382-amino-acid Slu7… Expand
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Highly Cited
2002
Highly Cited
2002
We report that the cyclophilin USA‐CyP is part of distinct complexes with two spliceosomal proteins and is involved in both steps… Expand
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Highly Cited
1998
Highly Cited
1998
Pre‐mRNA splicing takes place in two catalytic steps. The second step is poorly understood, especially in mammals. In yeast, the… Expand
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Highly Cited
1997
Highly Cited
1997
We show that the requirement for Prp18 during the second step of actin pre-mRNA splicing in vitro is dictated by the distance… Expand
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Highly Cited
1997
Highly Cited
1997
We have identified a human splicing factor required for the second step of pre-mRNA splicing. This new protein, hPrp18, is 30… Expand
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Highly Cited
1993
Highly Cited
1993
We have analyzed pre-mRNA splicing in yeast extracts immunodepleted of the PRP18 protein. We find that while the first step of… Expand
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Highly Cited
1993
Highly Cited
1993
The PRP18 gene, which had been identified in a screen for pre-mRNA splicing mutants in Saccharomyces cerevisiae, has been cloned… Expand
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