PRPF18 gene

Known as: hPrp18, pre-mRNA processing factor 18, PRPF18 
 
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
The assembly of the spliceosome involves dynamic rearrangements of interactions between snRNAs, protein components, and the pre… (More)
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Highly Cited
2009
Highly Cited
2009
The spliceosome is a ribonucleoprotein machine that removes introns from pre-mRNA in a two-step reaction. To investigate the… (More)
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2007
2007
Interaction of the ends of the exons with loop 1 of the U5 snRNA aligns the exons for ligation in the second step of pre-mRNA… (More)
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2003
2003
Saccharomyces cerevisiae PRP17 (CDC40) encodes a second-step pre-mRNA splicing factor with a role in cell division. The functions… (More)
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Highly Cited
2002
Highly Cited
2002
We report that the cyclophilin USA-CyP is part of distinct complexes with two spliceosomal proteins and is involved in both steps… (More)
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2002
2002
Slu7 and Prp18 act in concert during the second step of yeast pre-mRNA splicing. Here we show that the 382-amino-acid Slu7… (More)
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1998
1998
Pre-mRNA splicing takes place in two catalytic steps. The second step is poorly understood, especially in mammals. In yeast, the… (More)
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1997
1997
We show that the requirement for Prp18 during the second step of actin pre-mRNA splicing in vitro is dictated by the distance… (More)
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1993
1993
We have analyzed pre-mRNA splicing in yeast extracts immunodepleted of the PRP18 protein. We find that while the first step of… (More)
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1993
1993
The PRP18 gene, which had been identified in a screen for pre-mRNA splicing mutants in Saccharomyces cerevisiae, has been cloned… (More)
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