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PRO 2000

Known as: 2000 pro, PRO-2000, PRO2000 
 
National Institutes of Health

Papers overview

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2015
2015
Objectives Lignosulfonic acid (LA), a low-cost lignin-derived polyanionic macromolecule, was extensively studied for its anti-HIV… Expand
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Highly Cited
2011
Highly Cited
2011
Objective:To determine the safety and effectiveness of BufferGel and 0.5% PRO2000 microbicide gels for the prevention of male-to… Expand
Highly Cited
2010
Highly Cited
2010
Summary Background Innovative prevention strategies for HIV-1 transmission are urgently needed. PRO2000 vaginal gel was… Expand
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Highly Cited
2010
Highly Cited
2010
ABSTRACT The use of microbicides is a promising approach for the prevention of HIV-1 transmission. Unfortunately, various… Expand
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2010
2010
In sub-Saharan Africa the burden of HIV infection falls largely on women who represent about 60% of all people living with the… Expand
Highly Cited
2009
Highly Cited
2009
BACKGROUND The lack of biomarkers that are predictive of safety is a critical gap in the development of microbicides. The present… Expand
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2009
2009
Reduction of intramolecular disulfides in the HIV-1 envelope protein gp120 occurs after its binding to the CD4 receptor. Protein… Expand
Highly Cited
2008
Highly Cited
2008
Cellulose sulfate, a polyanionic compound derived from cotton, has been proposed as a topical microbicide to reduce the sexual… Expand
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2003
2003
The introduction of systemic chemotherapy improved significantly the prognosis of osteosarcoma. Despite this success… Expand
Highly Cited
2001
Highly Cited
2001
Background Vaginal agents which are antiviral and/or inhibit the entry of HIV into the cell could prevent heterosexual… Expand