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PRO 2000

Known as: 2000 pro, PRO-2000, PRO2000 
 
National Institutes of Health

Papers overview

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2014
2014
OBJECTIVES To estimate the effectiveness of candidate microbicides BufferGel and 0.5% PRO 2000 Gel (P) (PRO 2000) for prevention… Expand
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Highly Cited
2011
Highly Cited
2011
OBJECTIVE To determine the safety and effectiveness of BufferGel and 0.5% PRO2000 microbicide gels for the prevention of male-to… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Innovative prevention strategies for HIV-1 transmission are urgently needed. PRO2000 vaginal gel was efficacious… Expand
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2010
2010
Microbicides are products that can be applied to vaginal or rectal mucosa with the intent of preventing, or at least… Expand
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2009
2009
Reduction of intramolecular disulfides in the HIV-1 envelope protein gp120 occurs after its binding to the CD4 receptor. Protein… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND The lack of biomarkers that are predictive of safety is a critical gap in the development of microbicides. The present… Expand
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2008
2008
Indevus Pharmaceuticals Inc, under license from Paligent Inc, is developing PRO-2000, an antimicrobial gel for the prevention of… Expand
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2007
2007
Exposure of HIV-1 to dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN)-expressing B… Expand
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2003
2003
The introduction of systemic chemotherapy improved significantly the prognosis of osteosarcoma. Despite this success… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Vaginal agents which are antiviral and/or inhibit the entry of HIV into the cell could prevent heterosexual… Expand
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