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Empirical Bayes estimates of age-standardized relative risks for use in disease mapping.
A new approach using empirical Bayes estimation is proposed to map incidence and mortality from diseases such as cancer and the resulting estimators represent a weighted compromise between the SMR, the overall mean relative rate, and a local mean of the relative rate in nearby areas. Expand
Spontaneous viral clearance following acute hepatitis C infection: a systematic review of longitudinal studies
A systematic review was conducted of longitudinal studies of acute hepatitis C infection to improve the precision of the estimated rate of spontaneous viral clearance, and factors associated with viral clearance were female gender and acute clinical hepatitis C study population. Expand
The 15-Country Collaborative Study of Cancer Risk among Radiation Workers in the Nuclear Industry: Estimates of Radiation-Related Cancer Risks
This is the largest analytical epidemiological study of the effects of low-dose protracted exposures to ionizing radiation to date, and shows a strong healthy worker survivor effect in these cohorts. Expand
An empirical approach to the statistical analysis of mutagenesis data from the Salmonella test.
A formal method of deciding which points are on the initial linear part of the curve is described, and a statistical method is proposed for analyzing these points, which provides a very satisfactory, robust method for the standard analysis of Salmonella data. Expand
Estimating progression to cirrhosis in chronic hepatitis C virus infection
For persons who acquire HCV infection in young adulthood, less than 10% are estimated to develop cirrhosis within 20 years, suggesting community‐based cohort studies are likely to provide a more representative basis for estimating disease progression at a population level. Expand
Risk of cancer after low doses of ionising radiation: retrospective cohort study in 15 countries
Estimates of risk of cancer after protracted low doses of ionising radiation after nuclear workers in the largest study of nuclear workers ever conducted are higher than, but statistically compatible with, the risk estimates used for current radiation protection standards. Expand
Cancer incidence before and after kidney transplantation.
Comparing the incidence of cancer in patients receiving immune suppression after kidney transplantation with incidence in the same population in 2 periods before receipt of immune suppression suggests a broader than previously appreciated role of the interaction between the immune system and common viral infections in the etiology of cancer. Expand
Changes to AIDS dementia complex in the era of highly active antiretroviral therapy.
A proportional increase in ADC compared with other ADIs and a marked increase in the median CD4 cell count at ADC diagnosis have occurred since the introduction of HAART in Australia, suggesting that HAART has a lesser impact on ADC than on otherADIs, with the poor CNS penetration of many antiretroviral agents a possible explanation. Expand
Per-contact probability of HIV transmission in homosexual men in Sydney in the era of HAART
Despite the fact that a high proportion of HIV-infected men are on antiretroviral treatment and have undetectable viral load, the per-contact probability of HIV transmission due to UAI is similar to estimates reported from developed country settings in the pre-HAART era. Expand
Relation between HIV viral load and infectiousness: a model-based analysis
The analyses suggest that the risk of HIV transmission in heterosexual partnerships in the presence of effective treatment is low but non-zero and that the transmission risk in male homosexual partnerships is high over repeated exposures. Expand