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PRM-151

Known as: PRM-151/PTX2, Recombinant Human PTX2, Recombinant Human Serum Amyloid P/Pentraxin 2 
A fully recombinant form of the human pentraxin 2 (PTX2) protein with potential antifibrotic activity. Upon intravenous administration, recombinant… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

Homeodomain ProteinsRecombinant ProteinsSerum Amyloid P-Component

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Beyond JAK2 Inhibitors: A Systematic Review of Management Strategies for Myelofibrosis
Introduction Drugs that target activating mutations of Janus Kinase 2 (JAK2) have been the backbone of myelofibrosis (MF… 
2015
2015
Outcomes in Myelofibrosis Patients Completing 24 and 36 Weeks of Treatment with PRM-151
2014
2014
Phase 2 Trial of PRM-151, an Anti-Fibrotic Agent, in Patients with Myelofibrosis: Stage 1 Results
PRM-151 (PRM) is a recombinant form of Pentraxin-2, an endogenous human protein that acts at sites of tissue damage, inducing… 
Review
2014
Review
2014
Rationale for combination therapy in myelofibrosis.
2014
2014
Phase 2 trial of PRM-151, an antifibrotic agent, in patients with myelofibrosis: Stage 1 results.
7114 Background: PRM-151 (PRM) is a recombinant form of Pentraxin-2, an endogenous human protein that acts at sites of tissue… 
2013
2013
Characterization and stabilization of recombinant human protein pentraxin (rhPTX-2).
The potential human therapeutic protein pentraxin (PTX-2) is a large, glycosylated plasma protein consisting of five monomers… 
2011
2011
Recombinant Human Pentraxin-2 (PRM-151): Leveraging Nature’s Mechanism of Fibrocyte and Monocyte Regulation to Treat Disease
2011
2011
The Effects Of Recombinant Human Pentraxin-2, (PRM-151), On Circulating Fibrocytes In Idiopathic Pulmonary Fibrosis (IPF)
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