FAQ

Serum Amyloid P-Component

Known as: P Component, Amyloid, Serum Amyloid P Component, P-Component, Serum Amyloid 
Amyloid P component is a small, non-fibrillar glycoprotein found in normal serum and in all amyloid deposits. It has a pentagonal (pentaxin… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1957-2018
010020019572017

Related topics

Related topics

14 relations
APCS geneAmyloid P MeasurementAmyloid P component Ag:PrThr:Pt:Tiss:Ord:Immune stainProcess of secretion
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Narrower (3)

PRM-151PTX3 proteinpentraxin 3 (200-236)

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Serum Amyloid P-Component
physiological aspects
chemical synthesis
standards characteristics
Process of secretion
APCS gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Therapeutic Clearance of Amyloid by Antibodies to Serum Amyloid P Component.
BACKGROUND The amyloid fibril deposits that cause systemic amyloidosis always contain the nonfibrillar normal plasma protein… (More)
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Highly Cited
2010
Highly Cited
2010
Antibodies to human serum amyloid P component eliminate visceral amyloid deposits
Accumulation of amyloid fibrils in the viscera and connective tissues causes systemic amyloidosis, which is responsible for about… (More)
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Highly Cited
2002
Highly Cited
2002
Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis
The normal plasma protein serum amyloid P component (SAP) binds to fibrils in all types of amyloid deposits, and contributes to… (More)
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Highly Cited
1999
Highly Cited
1999
Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity
Serum amyloid P component (SAP), a highly conserved plasma protein named for its universal presence in amyloid deposits, is the… (More)
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Highly Cited
1997
Highly Cited
1997
Amyloid deposition is delayed in mice with targeted deletion of the serum amyloid P component gene
The tissue amyloid deposits that characterize systemic amyloidosis, Alzheimer's disease and the transmissible spongiform… (More)
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Highly Cited
1995
Highly Cited
1995
Serum amyloid P component prevents proteolysis of the amyloid fibrils of Alzheimer disease and systemic amyloidosis.
Extracellular deposition of amyloid fibrils is responsible for the pathology in the systemic amyloidoses and probably also in… (More)
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Highly Cited
1994
Highly Cited
1994
Structure of pentameric human serum amyloid P component
The three-dimensional structure of pentameric human serum amyloid P component at high resolution, the first reported for a… (More)
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1991
1991
Serum amyloid P component in chronic renal failure and dialysis.
A normal reference interval for serum amyloid P component (SAP) concentration in the serum was established in 500 healthy adult… (More)
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Highly Cited
1990
Highly Cited
1990
Evaluation of systemic amyloidosis by scintigraphy with 123I-labeled serum amyloid P component.
BACKGROUND In systemic amyloidosis the distribution and progression of disease have been difficult to monitor, because they can… (More)
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Highly Cited
1979
Highly Cited
1979
Binding of serum amyloid P-component (SAP) by amyloid fibrils.
Serum amyloid P-component (protein SAP) was found to bind in vitro to isolated amyloid fibrils of both primary and secondary… (More)
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