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PRKG2 gene

Known as: PRKGR2, PRKG2, cGKII 
This gene plays a role in signal transduction and the regulation of intestinal fluid secretion.
National Institutes of Health

Related topics

Related topics

4 relations
PRKG2 protein, humanPhosphorylationSerine/Threonine PhosphorylationSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Genetic variants of cGMP-dependent protein kinase genes and salt sensitivity of blood pressure: the GenSalt study
Genetic mechanisms involved in the susceptibility to salt sensitivity have not been completely clarified. This study aimed to… 
Review
2016
Review
2016
Therapeutic effect of CNP on renal osteodystrophy by antagonizing the FGF-23/MAPK pathway
Abstract Renal osteodystrophy (ROD) is highly prevalent in chronic kidney disease (CKD). Because most patients with ROD are… 
2014
2014
cGMP-dependent protein kinase type II knockout mice exhibit working memory impairments, decreased repetitive behavior, and increased anxiety-like traits
2014
2014
The Regulation of Synaptic Vesicle Recycling by cGMP-Dependent Protein Kinase Type II in Cerebellar Granule Cells under Strong and Sustained Stimulation
From the early periods of neurogenesis and migration, up until synaptogenesis, both nitric oxide (NO) and its downstream… 
2013
2013
Expanding the spectrum of microdeletion 4q21 syndrome: A partial phenotype with incomplete deletion of the minimal critical region and a new association with cleft palate and pierre robin sequence
Microdeletion 4q21 syndrome has been described in about a dozen patients with deletions ranging from 3.2 to 15.1 MB with similar… 
Highly Cited
2004
Highly Cited
2004
Cyclic GMP-dependent protein kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes.
The Komeda miniature rat Ishikawa (KMI) is a naturally occurring mutant caused by an autosomal recessive mutation mri, which… 
Review
2004
Review
2004
Mutation in cGMP-dependent protein kinase II causes dwarfism in a rat mutant KMI through uncoupling of proliferation and differentiation of chondrocytes
Longitudinal skeletal growth is achieved by an exquisite process known as endochondral ossification in the epiphyseal growth… 
2002
2002
The Electrolyte/Fluid Secretion Stimulatory Peptides Guanylin and Uroguanylin and Their Common Functional Coupling Proteins in the Rat Pancreas: A Correlative Study of Expression and Cell-Specific…
Introduction Guanylin and uroguanylin are intestinal or urine peptides that stimulate epithelial electrolyte/fluid secretion by… 
2002
2002
Autoinhibition and Isoform-specific Dominant Negative Inhibition of the Type II cGMP-dependent Protein Kinase*
In the absence of cyclic nucleotides, the cAMP-dependent protein kinase and cGMP-dependent protein kinases (cGKs) suppress… 
1998
1998
Long-Term Potentiation in the Hippocampal CA 1 Region of Mice Lacking cGMP-Dependent Kinases Is Normal and Susceptible to Inhibition of Nitric Oxide Synthase
Long-term potentiation (LTP) is a potential cellular mechanism for learning and memory. The retrograde messenger nitric oxide (NO… 
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