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PRKCA gene

Known as: protein kinase C alpha, PROTEIN KINASE C, ALPHA, Protein Kinase C, Alpha Gene 
This gene plays a role in numerous cellular processes such as adhesion, growth and volume control. It is also involved in memory function in the… 
National Institutes of Health

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Related topics

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Calcium BindingPRKCA protein, humanPhosphorylationPituitary Neoplasms

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PRKCA wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Copy number variation analysis and targeted NGS in 77 families with suspected Lynch syndrome reveals novel potential causative genes
In many families with suspected Lynch syndrome (LS), no germline mutation in the causative mismatch repair (MMR) genes is… 
2014
2014
Dynamic Modularity of Host Protein Interaction Networks in Salmonella Typhi Infection
Background Salmonella Typhi is a human-restricted pathogen, which causes typhoid fever and remains a global health problem in the… 
2013
2013
Crucial Roles of the Protein Kinases MK2 and MK3 in a Mouse Model of Glomerulonephritis
Elevated mitogen-activated protein kinase p38 (p38 MAPK) signaling has been implicated in various experimental and human… 
2013
2013
Interaction of polymorphisms in mitotic regulator genes with cigarette smoking and pancreatic cancer risk
Mitotic regulator genes have been associated with several cancers, however little is known about their possible association with… 
2010
2010
Evidence for rare and common genetic risk variants for schizophrenia at protein kinase C, alpha
We earlier reported a genome-wide significant linkage to schizophrenia at chromosome 17 that was identified in a single pedigree… 
Review
2007
Review
2007
Enzastaurin , a Protein Kinase C B ^ Selective Inhibitor , and Its PotentialApplicationasanAnticancer AgentinLungCancer
Enzastaurin, an oral serine/threonine kinase inhibitor, suppresses signaling throughprotein kinase C (PKC)-h and the… 
Highly Cited
2006
Highly Cited
2006
PRKCA and Multiple Sclerosis: Association in Two Independent Populations
Multiple sclerosis (MS) is a chronic disease of the central nervous system responsible for a large portion of neurological… 
1998
1998
Molecular cytogenetic mapping of 24 CEPH YACs and 24 gene-specific large insert probes to chromosome 17
Defining boundaries of chromosomal rearrangements at the molecular level would benefit from landmarks that link the cytogenetic… 
1996
1996
Cloning and characterisation of genes (pkc1 and pkcA) encoding protein kinase C homologues from Trichoderma reesei and Aspergillus niger.
Oligonucleotides, designed on the basis of conserved flanking amino acid sequence segments within the catalytic domain of… 
Highly Cited
1989
Highly Cited
1989
A protein kinase C cDNA without the regulatory domain is active after transfection in vivo in the absence of phorbol ester
We constructed mutant protein kinase C (PKC) cDNAs which expressed PKC activity in vivo in the absence of phorbol ester… 
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