PRKCA gene

Known as: protein kinase C alpha, PROTEIN KINASE C, ALPHA, Protein Kinase C, Alpha Gene 
This gene plays a role in numerous cellular processes such as adhesion, growth and volume control. It is also involved in memory function in the… (More)
National Institutes of Health

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8 relations
Calcium BindingPRKCA protein, humanPhosphorylationPituitary Neoplasms
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PRKCA wt Allele

Papers overview

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2013
2013
Identification of a novel, recurrent SLC44A1-PRKCA fusion in papillary glioneuronal tumor.
Mixed neuronal-glial tumors are rare and challenging to subclassify. One recently recognized variant, papillary glioneuronal… (More)
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2012
2012
Short-term weightlessness produced by parabolic flight maneuvers altered gene expression patterns in human endothelial cells.
This study focused on the effects of short-term microgravity (22 s) on the gene expression and morphology of endothelial cells… (More)
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2012
2012
PKCα is genetically linked to memory capacity in healthy subjects and to risk for posttraumatic stress disorder in genocide survivors.
Strong memory of a traumatic event is thought to contribute to the development and symptoms of posttraumatic stress disorder… (More)
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Highly Cited
2011
Highly Cited
2011
MicroRNA-328 is associated with (non-small) cell lung cancer (NSCLC) brain metastasis and mediates NSCLC migration.
Brain metastasis (BM) can affect ∼ 25% of nonsmall cell lung cancer (NSCLC) patients during their lifetime. Efforts to… (More)
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2009
2009
PRKCA: a positional candidate gene for body mass index and asthma.
Asthma incidence and prevalence are higher in obese individuals. A potential mechanistic basis for this relationship is… (More)
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2007
2007
Light Entrainment of the Mammalian Circadian Clock by a PRKCA-Dependent Posttranslational Mechanism
Light is the most potent stimulus for synchronizing endogenous circadian rhythms with external time. Photic clock resetting in… (More)
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2007
2007
A protein kinase C-encoding gene, pkcA, is essential to the viability of the filamentous fungus Aspergillus nidulans.
A protein kinase C (PKC)-encoding gene (pkcA) was isolated from the filamentous fungus Aspergillus nidulans. Although we… (More)
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2006
2006
PRKCA and Multiple Sclerosis: Association in Two Independent Populations
Multiple sclerosis (MS) is a chronic disease of the central nervous system responsible for a large portion of neurological… (More)
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1999
1999
Phase I Study of an Antisense Oligonucleotide to Protein Kinase C-α (ISIS 3521/CGP 64128A) in Patients with Cancer,
Protein kinase C (PKC) is an attractive target in cancer therapy. It is overexpressed in a variety of cancers, and nonspecific… (More)
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1989
1989
A protein kinase C cDNA without the regulatory domain is active after transfection in vivo in the absence of phorbol ester.
We constructed mutant protein kinase C (PKC) cDNAs which expressed PKC activity in vivo in the absence of phorbol ester… (More)
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