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PPME1 gene

Known as: PME1, PME-1, PPME1 
National Institutes of Health

Related topics

Related topics

1 relation
protein phosphatase methylesterase-1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
PP2A Inhibitor PME-1 Drives Kinase Inhibitor Resistance in Glioma Cells.
Glioblastoma multiforme lacks effective therapy options. Although deregulated kinase pathways are drivers of malignant… 
Highly Cited
2014
Highly Cited
2014
PME-1 modulates protein phosphatase 2A activity to promote the malignant phenotype of endometrial cancer cells.
Protein phosphatase 2A (PP2A) negatively regulates tumorigenic signaling pathways, in part, by supporting the function of tumor… 
2013
2013
IMP1 promotes choriocarcinoma cell migration and invasion through the novel effectors RSK2 and PPME1.
Highly Cited
2012
Highly Cited
2012
A functional pectin methylesterase inhibitor protein (SolyPMEI) is expressed during tomato fruit ripening and interacts with PME-1
A pectin methylesterase inhibitor (SolyPMEI) from tomato has been identified and characterised by a functional genomics approach… 
2012
2012
Glycogen synthase kinase‐3β regulates leucine‐309 demethylation of protein phosphatase‐2A via PPMT1 and PME‐1
Highly Cited
2009
Highly Cited
2009
PME-1 protects extracellular signal-regulated kinase pathway activity from protein phosphatase 2A-mediated inactivation in human malignant glioma.
Extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinase pathway activity is regulated by the antagonist… 
Highly Cited
2008
Highly Cited
2008
Folate Deficiency Induces In Vitro and Mouse Brain Region-Specific Downregulation of Leucine Carboxyl Methyltransferase-1 and Protein Phosphatase 2A Bα Subunit Expression That Correlate with Enhanced…
Altered folate homeostasis is associated with many clinical and pathological manifestations in the CNS. Notably, folate-mediated… 
Highly Cited
2008
Highly Cited
2008
Targeted Disruption of the PME-1 Gene Causes Loss of Demethylated PP2A and Perinatal Lethality in Mice
Background Phosphoprotein phosphatase 2A (PP2A), a major serine-threonine protein phosphatase in eukaryotes, is an oligomeric… 
Highly Cited
2008
Highly Cited
2008
Spatial control of protein phosphatase 2A (de)methylation.
Highly Cited
2004
Highly Cited
2004
An inactive protein phosphatase 2A population is associated with methylesterase and can be re-activated by the phosphotyrosyl phosphatase activator.
We have described recently the purification and cloning of PP2A (protein phosphatase 2A) leucine carboxylmethyltransferase. We… 
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