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PPAT wt Allele

Known as: Inorganic Pyrophosphatase 2 Gene, ATASE, GPAT 
Human PPAT wild-type allele is located within 4q12 and is approximately 42 kb in length. This allele, which encodes amidophosphoribosyltransferase… 
National Institutes of Health

Related topics

Related topics

5 relations
4q12Metal Ion BindingNucleotide BiosynthesisPPAT gene

Papers overview

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1999
1999
Mammalian cells expressing Escherichia coli O6-alkylguanine-DNA alkyltransferases are hypersensitive to dibromoalkanes.
The effect of expression of the DNA repair protein, O6-alkylguanine-DNA alkyltransferase, on the growth inhibitory effects of the… 
1996
1996
3-methyladenine-DNA-glycosylase and O6-alkyl guanine-DNA-alkyltransferase activities and sensitivity to alkylating agents in human cancer cell lines.
The activities and the expression of 3-methyladenine glycosylase (3-meAde gly) and O6-alkylguanine-DNA-alkyltransferase (O6 ATase… 
1995
1995
Differential expression of the o6‐alkylguanine‐DNA alkyltransferase gene in normal human breast and skin tissue: In situ mapping of cell type‐specific expression
O6‐Alkylguanine is a major toxic, mutagenic, and carcinogenic lesion in cellular DNA that is repaired by O6‐alkylguanine‐DNA… 
1994
1994
O6-alkylguanine-DNA alkyltransferase activity in schistosomiasis-associated human bladder cancer.
1992
1992
O6-alkylguanine-DNA-alkyltransferase activity and nitrosourea sensitivity in human cancer cell lines.
The DNA repair enzyme, O6-alkylguanine-DNA-alkyltransferase (ATase), is thought to be the principal mechanism controlling… 
1992
1992
Isolation and partial characterization of murine O6‐alkyiguanine‐DNA‐alkyltransferase: Comparative sequence and structural properties
A cDNA encoding murine O6‐alkylguanine‐DNA‐alkyltransferase (ATase) has been sequenced after isolation from total liver RNA by… 
1990
1990
Expression of a human O6-alkylguanine-DNA-alkyltransferase cDNA in human cells and transgenic mice.
A truncated human O6-alkylguanine-DNA-alkyltransferase (ATase) cDNA was ligated into an expression vector under the control of… 
Review
1989
Review
1989
Expression of the ogt gene in wild-type and ada mutants of E. coli.
O6-alkylguanine (O6-AlkG) DNA alkyltransferase (ATase) and alkylphosphotriester (AlkP) ATase activity have been quantitated… 
Highly Cited
1988
Highly Cited
1988
Transfection of murine multi-potent haemopoietic stem cells with an E. coli DNA alkyltransferase gene confers resistance to the toxic effects of alkylating agents.
O6-alkylguanine-DNA-alkyltransferase (ATase)-deficient murine haemopoietic stem cells were transfected, following electroporation… 
1986
1986
Increased rate of de novo purine synthesis and its mechanism in regenerating rat liver.
In regenerating rat liver at 12 h after a 70% hepatectomy, [14C]glycine incorporation to hepatic acid-soluble purines increased… 
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