Skip to search formSkip to main contentSkip to account menu

PPAT gene

Known as: Phosphoribosyl Pyrophosphate Amidotransferase Gene, PPAT, PRAT 
This gene plays a role in de novo purine nucleotide biosynthesis.
National Institutes of Health

Related topics

Related topics

6 relations
AmidophosphoribosyltransferaseMetal Ion BindingNucleotide BiosynthesisPPAT wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Discovery of Inhibitors of 4′-Phosphopantetheine Adenylyltransferase (PPAT) To Validate PPAT as a Target for Antibacterial Therapy
ABSTRACT Inhibitors of 4′-phosphopantetheine adenylyltransferase (PPAT) were identified through high-throughput screening of the… 
Highly Cited
2012
Highly Cited
2012
Tumor Cell-educated Periprostatic Adipose Tissue Acquires an Aggressive Cancer-promoting Secretory Profile
Background/Aims: The microenvironment produces important factors that are crucial to prostate cancer (PCa) progression. However… 
Highly Cited
2010
Highly Cited
2010
GPAT3 and GPAT4 are regulated by insulin-stimulated phosphorylation and play distinct roles in adipogenesis[S]
Acyl-CoA:glycerol-3-phosphate acyltransferase (GPAT) catalyzes the first step during de novo synthesis of glycerolipids. Mammals… 
Highly Cited
2009
Highly Cited
2009
Arabidopsis thaliana GPAT8 and GPAT9 are localized to the ER and possess distinct ER retrieval signals: functional divergence of the dilysine ER retrieval motif in plant cells.
2008
2008
A study in molecular contingency: glutamine phosphoribosylpyrophosphate amidotransferase is a promiscuous and evolvable phosphoribosylanthranilate isomerase.
Highly Cited
2007
Highly Cited
2007
Overexpression of glycerol-3-phosphate acyltransferase gene improves chilling tolerance in tomato
A tomato (Lycopersicon esculentum Mill.) glycerol-3-phosphate acyltransferase gene (LeGPAT) was isolated. The deduced amino acid… 
Highly Cited
2005
Highly Cited
2005
Preservation and High Sequence Conservation of Satellite DNAs Suggest Functional Constraints
Due to a high evolutionary turnover many satellite DNAs are restricted to a group of closely related species. Here we demonstrate… 
2003
2003
Inhibitors of phosphopantetheine adenylyltransferase.
Highly Cited
1999
Highly Cited
1999
The crystal structure of a novel bacterial adenylyltransferase reveals half of sites reactivity
Phosphopantetheine adenylyltransferase (PPAT) is an essential enzyme in bacteria that catalyses a rate‐limiting step in coenzyme… 
1983
1983
Cloning of the Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase gene in Escherichia coli. Nucleotide sequence determination and properties of the plasmid-encoded enzyme.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)