Skip to search formSkip to main contentSkip to account menu

PPAT gene

Known as: Phosphoribosyl Pyrophosphate Amidotransferase Gene, PPAT, PRAT 
This gene plays a role in de novo purine nucleotide biosynthesis.
National Institutes of Health

Related topics

Related topics

6 relations
AmidophosphoribosyltransferaseMetal Ion BindingNucleotide BiosynthesisPPAT wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Computational investigations of gram-negative bacteria phosphopantetheine adenylyltransferase inhibitors using 3D-QSAR, molecular docking and molecular dynamic simulations
Abstract Phosphopantetheine adenylyltransferase (PPAT) has been recognized as a promising target to develop novel antimicrobial… 
2015
2015
Functional Complementation Analyses Reveal that the Single PRAT Family Protein of Trypanosoma brucei Is a Divergent Homolog of Tim17 in Saccharomyces cerevisiae
ABSTRACT Trypanosoma brucei, a parasitic protozoan that causes African trypanosomiasis, possesses a single member of the… 
2013
2013
In search of actionable targets for agrigenomics and microalgal biofuel production: sequence-structural diversity studies on algal and higher plants with a focus on GPAT protein.
The triacylglycerol (TAG) pathway provides several targets for genetic engineering to optimize microalgal lipid productivity… 
2007
2007
Chemical Genetic Identification of Glutamine Phosphoribosylpyrophosphate Amidotransferase as the Target for a Novel Bleaching Herbicide in Arabidopsis[W][OA]
A novel phenyltriazole acetic acid compound (DAS734) produced bleaching of new growth on a variety of dicotyledonous weeds and… 
2003
2003
Arabidopsis AtGPAT 1 , a Member of the Membrane-Bound Glycerol-3-Phosphate Acyltransferase Gene Family , Is Essential for Tapetum Differentiation and Male Fertility
Membrane-bound glycerol-3-phosphate acyltransferase (GPAT; EC 2.3.1.15) mediates the initial step of glycerolipid biosynthesis in… 
1995
1995
Control of de novo purine biosynthesis genes in ureide-producing legumes: induction of glutamine phosphoribosylpyrophosphate amidotransferase gene and characterization of its cDNA from soybean and…
Soybean (Glycine max) and mothbean (Vigna aconitifolia) cDNA clones encoding glutamine phosphoribosylpyrophosphate… 
1994
1994
Molecular and genetic analyses of Drosophila Prat, which encodes the first enzyme of de novo purine biosynthesis.
The Drosophila Prat gene encodes phosphoribosylamidotransferase (PRAT), the enzyme that performs the first committed step of the… 
1992
1992
Avian glutamine phosphoribosylpyrophosphate amidotransferase propeptide processing and activity are dependent upon essential cysteine residues.
1983
1983
Cloning of the Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase gene in Escherichia coli. Nucleotide sequence determination and properties of the plasmid-encoded enzyme.
1976
1976
Potentiation by guanine nucleosides of the growth-inhibitory effects of adenosine analogs on L1210 and sarcoma 180 cells in culture.
The growth-inhibitory effect of 6-methylmercaptopurine riboside (MMPR) against leukemia L1210 cells in culture was dramatically… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)