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PPARGC1A wt Allele

Known as: LEM6, PGC-1(alpha), PPARGC1 
Human PPARGC1A wild-type allele is located in the vicinity of 4p15.1 and is approximately 149 kb in length. This allele, which encodes peroxisome… 
National Institutes of Health

Related topics

Related topics

12 relations
4p15.1Adipocytokine Signaling PathwayDigestionGluconeogenesis Induction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Association of a PPARD polymorphism with human physical performance
Peroxisome proliferator-activated receptor δ (PPARδ) regulates the expression of genes involved in lipid and carbohydrate… 
Highly Cited
2006
Highly Cited
2006
Peroxisome proliferator-activated receptor-alpha and -gamma mRNA levels are reduced in chronic hepatitis C with steatosis and genotype 3 infection.
BACKGROUND Steatosis in chronic hepatitis C is associated with inflammation and accelerated fibrogenesis. AIM To assess the… 
2006
2006
Peroxisome proliferator-activated receptor delta (PPARdelta) activation protects H9c2 cardiomyoblasts from oxidative stress-induced apoptosis.
OBJECTIVE Activation of peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma plays beneficial roles in… 
2006
2006
PPARγ antagonists reverse the inhibition of neural antigen-specific Th1 response and experimental allergic encephalomyelitis by Ciglitazone and 15-Deoxy-Δ12,14-Prostaglandin J2
Highly Cited
2005
Highly Cited
2005
15-DEOXY-Δ12,14-PROSTAGLANDIN J2 (15D-PGJ2), A PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR γ LIGAND, REDUCES TISSUE LEUKOSEQUESTRATION AND MORTALITY IN ENDOTOXIC SHOCK
Peroxisome proliferator-activated receptor-γ (PPARγ) is a nuclear receptor that requires ligand activation for transcription… 
Highly Cited
2005
Highly Cited
2005
PPARγ antagonists exacerbate neural antigen-specific Th1 response and experimental allergic encephalomyelitis
Highly Cited
2004
Highly Cited
2004
Peroxisome proliferator activated‐receptor agonism and left ventricular remodeling in mice with chronic myocardial infarction
Peroxisome proliferator activated receptor γ (PPARγ) has been implicated in several cellular pathways assumed to beneficially… 
Highly Cited
2004
Highly Cited
2004
Tyrosine agonists reverse the molecular defects associated with dominant-negative mutations in human peroxisome proliferator-activated receptor gamma.
Loss-of-function mutations in the ligand-binding domain of human peroxisome proliferator-activated receptor gamma (PPARgamma) are… 
Review
2001
Review
2001
Peroxisome proliferator-activated receptors: roles in tumorigenesis and chemoprevention in human cancer
Peroxisome proliferator-activated receptors are nuclear receptors that were isolated for their ability to modulate lipid… 
2000
2000
The Pro12Ala variant of peroxisome proliferator-activated receptor-gamma2 (PPAR-gamma2) is associated with measures of obesity in Mexican Americans.
Peroxisome proliferator-activated receptors (PPAR) are transcription factors that regulate adipocyte differentiation and gene… 
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