Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 217,273,827 papers from all fields of science
Search
Sign In
Create Free Account
PPARGC1A wt Allele
Known as:
LEM6
, PGC-1(alpha)
, PPARGC1
Expand
Human PPARGC1A wild-type allele is located in the vicinity of 4p15.1 and is approximately 149 kb in length. This allele, which encodes peroxisome…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
12 relations
4p15.1
Adipocytokine Signaling Pathway
Digestion
Gluconeogenesis Induction
Expand
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice
Zhanguo Gao
,
Jun-yi Yin
,
+5 authors
Jianping Ye
Diabetes
2009
Corpus ID: 16505212
OBJECTIVE We examined the role of butyric acid, a short-chain fatty acid formed by fermentation in the large intestine, in the…
Expand
Review
2006
Review
2006
Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism.
C. Handschin
,
B. Spiegelman
Endocrine reviews
2006
Corpus ID: 34573509
Many biological programs are regulated at the transcriptional level. This is generally achieved by the concerted actions of…
Expand
Review
2003
Review
2003
Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator.
P. Puigserver
,
B. Spiegelman
Endocrine reviews
2003
Corpus ID: 35074591
Investigations of biological programs that are controlled by gene transcription have mainly studied the regulation of…
Expand
Highly Cited
2003
Highly Cited
2003
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
M. Patti
,
A. Butte
,
+14 authors
L. Mandarino
Proceedings of the National Academy of Sciences…
2003
Corpus ID: 21642145
Type 2 diabetes mellitus (DM) is characterized by insulin resistance and pancreatic β cell dysfunction. In high-risk subjects…
Expand
Highly Cited
2003
Highly Cited
2003
Adipose-specific peroxisome proliferator-activated receptor γ knockout causes insulin resistance in fat and liver but not in muscle
Weimin He
,
Y. Barak
,
+7 authors
R. Evans
Proceedings of the National Academy of Sciences…
2003
Corpus ID: 8896189
Syndrome X, typified by obesity, insulin resistance (IR), dyslipidemia, and other metabolic abnormalities, is responsive to…
Expand
Review
2002
Review
2002
The mechanisms of action of PPARs.
J. Berger
,
D. Moller
Annual Review of Medicine
2002
Corpus ID: 11459441
The peroxisome proliferator-activated receptors (PPARs) are a group of three nuclear receptor isoforms, PPAR gamma, PPAR alpha…
Expand
Highly Cited
2000
Highly Cited
2000
Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis.
J. J. Lehman
,
P. Barger
,
A. Kovács
,
J. Saffitz
,
D. Medeiros
,
D. Kelly
Journal of Clinical Investigation
2000
Corpus ID: 26694726
Cardiac mitochondrial function is altered in a variety of inherited and acquired cardiovascular diseases. Recent studies have…
Expand
Highly Cited
2000
Highly Cited
2000
The Coactivator PGC-1 Cooperates with Peroxisome Proliferator-Activated Receptor α in Transcriptional Control of Nuclear Genes Encoding Mitochondrial Fatty Acid Oxidation Enzymes
Rick B. Vega
,
J. Huss
,
D. Kelly
Molecular and Cellular Biology
2000
Corpus ID: 15680088
ABSTRACT Peroxisome proliferator-activated receptor α (PPARα) plays a key role in the transcriptional control of genes encoding…
Expand
Highly Cited
1999
Highly Cited
1999
Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting
S. Kersten
,
J. Seydoux
,
J. Peters
,
F. Gonzalez
,
B. Desvergne
,
W. Wahli
1999
Corpus ID: 64782637
Prolonged deprivation of food induces dramatic changes in mammalian metabolism, including the release of large amounts of fatty…
Expand
Highly Cited
1994
Highly Cited
1994
Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor.
P. Tontonoz
,
E. Hu
,
B. Spiegelman
Cell
1994
Corpus ID: 13429074
Peroxisome proliferator-activated receptor gamma 2 (PPAR gamma 2) is an adipocyte-specific nuclear hormone receptor that has…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE