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PPARGC1A wt Allele

Known as: LEM6, PGC-1(alpha), PPARGC1 
Human PPARGC1A wild-type allele is located in the vicinity of 4p15.1 and is approximately 149 kb in length. This allele, which encodes peroxisome… 
National Institutes of Health

Related topics

Related topics

12 relations
4p15.1Adipocytokine Signaling PathwayDigestionGluconeogenesis Induction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Brief intense interval exercise activates AMPK and p38 MAPK signaling and increases the expression of PGC-1alpha in human skeletal muscle.
From a cell signaling perspective, short-duration intense muscular work is typically associated with resistance training and… 
Highly Cited
2008
Highly Cited
2008
Molecular, biochemical and functional characterizations of C1q/TNF family members: adipose-tissue-selective expression patterns, regulation by PPAR-gamma agonist, cysteine-mediated oligomerizations…
The insulin-sensitizing hormone, adiponectin, belongs to the expanding C1q/TNF (tumour necrosis factor) family of proteins. We… 
Review
2006
Review
2006
Environmental obesogens: organotins and endocrine disruption via nuclear receptor signaling.
Over the last two decades, the incidence of obesity and associated metabolic syndrome diseases has risen dramatically, becoming a… 
Highly Cited
2005
Highly Cited
2005
Peroxisome Proliferator-activated Receptor-γ Co-activator 1α-mediated Metabolic Remodeling of Skeletal Myocytes Mimics Exercise Training and Reverses Lipid-induced Mitochondrial Inefficiency*
Peroxisome proliferator-activated receptor-γ co-activator 1α (PGC1α) is a promiscuous co-activator that plays a key role in… 
Highly Cited
2005
Highly Cited
2005
PGC-1α regulates the mitochondrial antioxidant defense system in vascular endothelial cells
Highly Cited
2003
Highly Cited
2003
Peroxisome Proliferator-Activated Receptor Gamma (PPAR&ggr;) Expression Is Decreased in Pulmonary Hypertension and Affects Endothelial Cell Growth
Abstract— PPAR&ggr; is a member of a family of nuclear receptors/ligand–dependent transcription factors, which bind to hormone… 
Highly Cited
2001
Highly Cited
2001
PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
Peroxisome proliferator-activated receptor-γ (PPAR-γ) is highly expressed in lipid-accumulating macrophages of the coronary… 
Highly Cited
2000
Highly Cited
2000
Effects of ligand activation of peroxisome proliferator-activated receptor gamma in human prostate cancer.
Peroxisome proliferator-activated receptor gamma (PPARgamma) is a nuclear hormone receptor that plays a key role in the… 
Highly Cited
1999
Highly Cited
1999
Regulation of Peroxisome Proliferator-Activated Receptor γ Expression by Adipocyte Differentiation and Determination Factor 1/Sterol Regulatory Element Binding Protein 1: Implications for Adipocyte…
ABSTRACT Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear receptor implicated in adipocyte differentiation and… 
Review
1996
Review
1996
Peroxisome proliferator-activated receptors: a nuclear receptor signaling pathway in lipid physiology.
Peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors that belong to the steroid/thyroid… 
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