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POLB gene

Known as: POLYMERASE, DNA, BETA, polymerase (DNA) beta, POLB 
This gene is involved in DNA repair necessary for DNA maintenance, replication, recombination, and drug resistance.
National Institutes of Health

Related topics

Related topics

7 relations
Base Excision RepairDNA Polymerase Beta, humanDNA Polymerase betaDNA Replication

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Nucleation of DNA repair factors by FOXA1 links DNA demethylation to transcriptional pioneering
FOXA1 functions in epigenetic reprogramming and is described as a 'pioneer factor'. However, exactly how FOXA1 achieves these… 
2015
2015
Clinical Significance of a Point Mutation in DNA Polymerase Beta (POLB) Gene in Gastric Cancer
Gastric cancer (GC) is a major cause of global cancer mortality. Genetic variations in DNA repair genes can modulate DNA repair… 
2012
2012
Characterization of DNA Primase Complex Isolated from the Archaeon, Thermococcus kodakaraensis*
Background: Eukaryotic primase initiates replication by forming oligoribonucleotides that are elongated by DNA polymerases… 
Highly Cited
2010
Highly Cited
2010
DNA Polymerases as Potential Therapeutic Targets for Cancers Deficient in the DNA Mismatch Repair Proteins MSH2 or MLH1
Highly Cited
2009
Highly Cited
2009
DNA Repair Gene Polymorphisms and Risk of Pancreatic Cancer
Purpose: The current research was undertaken to examine the association between genetic variations in DNA repair and pancreatic… 
2009
2009
A platinum agent resistance gene, POLB, is a prognostic indicator in colorectal cancer
Recent progress in chemotherapy with platinum agents has improved clinical outcome in colorectal cancer (CRC), but there are no… 
2008
2008
Maintaining replication fork integrity in UV-irradiated Escherichia coli cells.
Highly Cited
2007
Highly Cited
2007
Genetic variation in the base excision repair pathway and bladder cancer risk
Genetic polymorphisms in DNA repair genes may impact individual variation in DNA repair capacity and alter cancer risk. In order… 
2007
2007
Effects of base excision repair gene polymorphisms on pancreatic cancer survival
To explore the association between single nucleotide polymorphisms of DNA repair genes and overall survival of patients with… 
Highly Cited
2005
Highly Cited
2005
Characterization and spontaneous mutation of a novel gene, polE, involved in pellicle formation in Acetobacter tropicalis SKU1100.
Acetobacter tropicalis SKU1100 produces a pellicle polysaccharide, consisting of galactose, glucose and rhamnose, which attaches… 
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