Genetic variation in the base excision repair pathway and bladder cancer risk

@article{Figueroa2006GeneticVI,
  title={Genetic variation in the base excision repair pathway and bladder cancer risk},
  author={Jonine D Figueroa and N{\'u}ria Malats and Francisco X Real and Debra T. Silverman and Manolis Kogevinas and Stephen C. Chanock and Robert Welch and Mustafa Dosemeci and Adonina Tard{\'o}n and Consol Serra and Alfredo Carrato and Reina Garc{\'i}a-Closas and Gemma Casta{\~n}o-Vinyals and Nathaniel Rothman and Montserrat Garc{\'i}a-Closas},
  journal={Human Genetics},
  year={2006},
  volume={121},
  pages={233-242}
}
Genetic polymorphisms in DNA repair genes may impact individual variation in DNA repair capacity and alter cancer risk. In order to examine the association of common genetic variation in the base-excision repair (BER) pathway with bladder cancer risk, we analyzed 43 single nucleotide polymorphisms (SNPs) in 12 BER genes (OGG1, MUTYH, APEX1, PARP1, PARP3, PARP4, XRCC1, POLB, POLD1, PCNA, LIG1, and LIG3). Using genotype data from 1,150 cases of urinary bladder transitional cell carcinomas and 1… CONTINUE READING

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DNA repair gene

  • G Matullo, S Guarrera, +5 authors P Vineis
  • 2001
Highly Influential
7 Excerpts

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