PNKP gene

Known as: polynucleotide kinase 3'-phosphatase, DNA KINASE, POLYNUCLEOTIDE KINASE 3-PRIME PHOSPHATASE 
 
National Institutes of Health

Papers overview

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2012
2012
We present a neurodegenerative disorder starting in early childhood of two brothers consisting of severe progressive… (More)
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2011
2011
XRCC1 is a scaffold protein capable of interacting with several DNA repair proteins. Here we provide evidence for the presence of… (More)
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Highly Cited
2010
Highly Cited
2010
Maintenance of DNA integrity is crucial for all cell types, but neurons are particularly sensitive to mutations in DNA repair… (More)
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Highly Cited
2008
Highly Cited
2008
Inhibitors of poly (ADP-ribose)-polymerase-1 (PARP) are highly lethal to cells with deficiencies in BRCA1, BRCA2 or other… (More)
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Highly Cited
2001
Highly Cited
2001
XRCC1 protein is required for DNA single-strand break repair and genetic stability but its biochemical role is unknown. Here, we… (More)
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1999
1999
Mammalian polynucleotide kinases catalyze the 5'-phosphorylation of nucleic acids and can have associated 3'-phosphatase activity… (More)
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Highly Cited
1994
Highly Cited
1994
We have isolated a large number of polynucleotide kinase ribozymes from a pool of RNA molecules consisting of an ATP-binding… (More)
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Highly Cited
1990
Highly Cited
1990
Many plants, as well as other organisms, accumulate betaine (N,N,N-trimethylglycine) as a nontoxic or protective osmolyte under… (More)
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1986
1986
To elucidate further the molecular basis of the specific regulatory mechanism modulating the expression of the genes implicated… (More)
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Highly Cited
1983
Highly Cited
1983
The pathogenicity of fixed rabies virus strains for adult mice depends on the presence of an antigenic determinant on the viral… (More)
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