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PMS2 gene

Known as: PMS1 homolog 2, mismatch repair system component, HNPCC4, MLH4 
This gene is involved in mismatch repair and mutations in the gene result in hereditary non-polyposis colon cancer 4.
National Institutes of Health

Papers overview

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2017
2017
The clinical spectrum of germline mismatch repair (MMR) gene variants continues increasing, encompassing Lynch syndrome… Expand
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2015
2015
Microsatellite instability (MSI) has been observed within tumors and found to be closely associated with the degree of malignancy… Expand
2013
2013
To the Editor: Lynch syndrome (LS) (MIM#276300) is a cancer predisposition condition resulting from mutations within the DNA… Expand
2011
2011
Lynch syndrome is characterized by mutations in the mismatch repair genes MLH1, MSH2, MSH6, and PMS2. In PMS2, detection of… Expand
2005
2005
The formation of binary complexes of Cr(III) and Fe(III) with a tripodal ligand cis,cis-1,3,5-tris(methylamino)cyclohexane (tmach… Expand
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Highly Cited
2004
Highly Cited
2004
The MutLα heterodimer formed by mismatch repair (MMR) proteins MLH1 and PMS2 is a major component of the MMR complex, yet… Expand
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2001
2001
The equilibria in the system VO2+ +oxidized glutathione in aqueous solution have been studied in the pH range 2-11 by a… Expand
Review
1999
Review
1999
Somatic hypermutation of Ig genes is probably dependent on transcription of the target gene via a mutator factor associated with… Expand
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Highly Cited
1998
Highly Cited
1998
Mice homozygous for a disrupted allele of the mismatch repair gene Pms2 have a mutator phenotype. When this allele is crossed… Expand