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PMS2 gene

Known as: PMS1 homolog 2, mismatch repair system component, HNPCC4, MLH4 
This gene is involved in mismatch repair and mutations in the gene result in hereditary non-polyposis colon cancer 4.
National Institutes of Health

Papers overview

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2017
2017
The clinical spectrum of germline mismatch repair (MMR) gene variants continues increasing, encompassing Lynch syndrome… Expand
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2015
2015
Microsatellite instability (MSI) has been observed within tumors and found to be closely associated with the degree of malignancy… Expand
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2013
2013
To the Editor: Lynch syndrome (LS) (MIM#276300) is a cancer predisposition condition resulting from mutations within the DNA… Expand
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2011
2011
Lynch syndrome is characterized by mutations in the mismatch repair genes MLH1, MSH2, MSH6, and PMS2. In PMS2, detection of… Expand
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2005
2005
The formation of binary complexes of Cr(III) and Fe(III) with a tripodal ligand cis,cis-1,3,5-tris(methylamino)cyclohexane (tmach… Expand
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Highly Cited
2004
Highly Cited
2004
The MutLalpha heterodimer formed by mismatch repair (MMR) proteins MLH1 and PMS2 is a major component of the MMR complex, yet… Expand
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2001
2001
The equilibria in the system VO2+ +oxidized glutathione in aqueous solution have been studied in the pH range 2-11 by a… Expand
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Review
1999
Review
1999
Somatic hypermutation of Ig genes is probably dependent on transcription of the target gene via a mutator factor associated with… Expand
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Highly Cited
1998
Highly Cited
1998
Mice homozygous for a disrupted allele of the mismatch repair gene Pms2 have a mutator phenotype. When this allele is crossed… Expand
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