Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

PML/RARA Fusion Protein

Known as: PML-RAR Protein, Inducer of Acute Promyelocytic Leukemia, PML-RARalpha Fusion Protein 
A fusion protein (797 aa, ~106 kDa) that is encoded by the PML/RARA fusion gene. This protein contains the B-box and the RING-finger domain from… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Arsenic on the Fingers Arsenic, an ancient drug used in traditional Chinese medicine, has attracted wide interest because it has… Expand
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Promoting Apoptosis During acute disease, the promyelocytic leukemia (PML) protein becomes fused to another protein as a result… Expand
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Promyelocytic leukemia (PML) is the organizer of nuclear matrix domains, PML nuclear bodies (NBs), with a proposed role in… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
BACKGROUND Two reports from China have suggested that arsenic trioxide can induce complete remissions in patients with acute… Expand
Is this relevant?
Highly Cited
1996
Highly Cited
1996
It has been shown recently in China that arsenic trioxide (As2O3) is a very effective treatment for acute promyelocytic leukemia… Expand
  • figure 1
  • figure 5
  • figure 3
  • figure 4
  • figure 6
Is this relevant?
Highly Cited
1995
Highly Cited
1995
The PML protein was first identified as part of a fusion product with the retinoic acid receptor alpha (RAR alpha), resulting… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Acute promyelocytic leukemia (APL) is characterized by a specific t(15;17) translocation that fuses the retinoic acid receptor… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Acute promyelocytic leukemia is a clonal expansion of hematopoietic precursors blocked at the promyelocytic stage. The… Expand
Is this relevant?
Highly Cited
1991
Highly Cited
1991
A unique mRNA produced in leukemic cells from a t(15;17) acute promyelocytic leukemia (APL) patient encodes a fusion protein… Expand
  • figure 1
  • figure 3
  • figure 4
  • figure 6
  • figure 7
Is this relevant?
Highly Cited
1991
Highly Cited
1991
We have previously shown that the t(15;17) translocation specifically associated with acute promyelocytic leukemia (APL) fuses… Expand
Is this relevant?