PIK3CD gene

Known as: PIK3CD, p110D, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 
This gene plays a role in the initiation of second messenger signaling.
National Institutes of Health

Papers overview

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2017
2017
Activated PI3K Delta Syndrome (APDS) is a primary immunodeficiency disease caused by activating mutations in either the leukocyte… (More)
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Highly Cited
2014
Highly Cited
2014
Autosomal dominant gain of function mutations in the gene encoding PI3K p110δ were recently associated with a novel combined… (More)
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2014
2014
PURPOSE To determine the prognostic significance of miR-663 in glioblastoma, its effect in tumor progression, and the underlying… (More)
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2014
2014
Colorectal cancer (CRC) is the third most common cancer in the USA. MicroRNAs play important roles in the pathogenesis of CRC. In… (More)
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2014
2014
Gain of function (GOF) mutation in the p110δ catalytic subunit of the phosphatidylinositol-3-OH kinase (PIK3CD) is the cause of a… (More)
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2014
2014
OBJECTIVES Increasing evidence has suggested the close relationship between microRNAs (miRNAs) dysregulation and the… (More)
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2013
2013
BACKGROUND/AIMS MicroRNAs (miRNAs) play key roles in tumor metastasis. The aim of this study was to determine the regulation and… (More)
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2012
Highly Cited
2012
UNLABELLED MicroRNAs (miRNAs) are known to be involved in carcinogenesis and tumor progression in hepatocellular carcinoma (HCC… (More)
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2012
2012
PI3Ks (phosphoinositide 3-kinases) are signalling molecules and drug targets with important biological functions, yet the… (More)
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Highly Cited
2003
Highly Cited
2003
Glioblastomas frequently carry mutations in the PTEN tumor suppressor gene on 10q23.3. The tumor suppressor properties of Pten… (More)
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