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Hand-arm vibration syndrome with use of anti-vibration chain saws: 19-year follow-up study of forestry workers
TLDR
The prevalence of active vibration white finger (VWF) constantly decreased and numbness also associated with upper extremity musculoskeletal disorders and the cumulative exposure to vibration among a cohort of forestry workers.
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Ménière's disease: a reappraisal supported by a variable latency of symptoms and the MRI visualisation of endolymphatic hydrops
TLDR
It is suggested that a 3T MRI measurement should be carried out in patients with sensory-neural hearing loss, vertigo and tinnitus, 4 h after the intravenous injection of a gadolinium-contrast agent to verify the inner ear pathology.
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What is Menière’s disease? A contemporary re-evaluation of endolymphatic hydrops
TLDR
It is indicated that endolymphatic hydrops is responsible not only for the full-blown clinical triad of simultaneous attacks of auditory and vestibular dysfunction, but also for other clinical presentations such as “vestibular” and “cochlear Menière’s disease”.
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Novel endosomolytic peptides for enhancing gene delivery in nanoparticles.
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Gadolinium Uptake in the Rat Inner Ear Perilymph Evaluated With 4.7 T MRI: A Comparison Between Transtympanic Injection and Gelatin Sponge-Based Diffusion Through the Round Window Membrane
TLDR
Considering its simplicity, TTI is more practical for use in the clinic for the administration of substances to the inner ear, although it provided less efficient uptake in the apex than GelD40.
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Distribution of lipid nanocapsules in different cochlear cell populations after round window membrane permeation.
TLDR
The results suggest that LNCs are potential vectors for drug delivery into the spiral ganglion cells, nerve fibers, hair cells, and spiral ligament, though infrequently.
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In Vivo Visualization of Endolymphatic Hydrops in Guinea Pigs: Magnetic Resonance Imaging Evaluation at 4.7 Tesla
TLDR
Endolymphatic hydrops can be visualized with high-resolution MRI by means of Gd-DTPA-BMA, and it is possible to quantify the extent of endolymphic hydrops, according to the surface area of 3 partitions of the cochlea.
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Nuclear entry of hyperbranched polylysine nanoparticles into cochlear cells
TLDR
The results suggest that HPNPs are potentially an ideal carrier for gene delivery into the cochlea.
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Vibration induced hearing loss in guinea pig cochlea: expression of TNF-α and VEGF
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Communication between the Perilymphatic Scalae and Spiral Ligament Visualized by in vivo MRI
TLDR
Gd-DTPA-BMA is transported from the RW to the semicircular canal, the scala tympani and scala vestibuli without passing the helicotrema, and taken into the perilymphatic space with 4.7-T MRI in an animal study and 1.5-T in humans.
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