Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

PIK3CB wt Allele

Known as: P110BETA, PI3K, p110-Beta 
Human PIK3CB wild-type allele is located in the vicinity of 3q22.3 and is approximately 105 kb in length. This allele, which encodes… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
The class I(A) phosphatidylinsositol 3-kinases (PI3Ks) form a critical node in the insulin metabolic pathway; however, the… Expand
  • figure 1
  • figure 2
  • figure 4
Highly Cited
2010
Highly Cited
2010
Therapeutic inhibitors are being developed against the phosphoinositide 3-kinase (PI3K) pathway, the deregulation of which drives… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Highly Cited
2009
Highly Cited
2009
Several phosphoinositide 3-kinase (PI3K) catalytic subunit inhibitors are currently in clinical trial. We therefore sought to… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Highly Cited
2009
Highly Cited
2009
Phosphatidylinositol 3-kinase (PI3K) isoforms PI3Kbeta and PI3Kgamma are implicated in platelet adhesion, activation, and… Expand
  • figure 1
  • figure 2
Highly Cited
2008
Highly Cited
2008
The phosphoinositide 3-kinase p110β subunit has noncatalytic functions; its catalytic activity is pertinent to both diabetes and… Expand
Highly Cited
2007
Highly Cited
2007
Recent genetic knock-in and pharmacological approaches have suggested that, of class IA PI3Ks (phosphatidylinositol 3-kinases… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Highly Cited
2006
Highly Cited
2006
Phosphoinositide 3-kinases (PI3-Ks) are an important emerging class of drug targets, but the unique roles of PI3-K isoforms… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
2006
Highly Cited
2006
Class I phosphoinositide 3-kinase contains four isoforms of the catalytic subunit, p110alpha, -beta, -gamma, and -delta. At… Expand
Highly Cited
2005
Highly Cited
2005
The PIK3CA gene encoding the p110alpha subunit of Class IA phosphatidylinositol 3-kinases (PI3Ks) is frequently mutated in human… Expand
Highly Cited
2005
Highly Cited
2005
Platelet activation at sites of vascular injury is essential for the arrest of bleeding; however, excessive platelet accumulation… Expand