PIK3CB wt Allele

Known as: P110BETA, PI3K, p110-Beta 
Human PIK3CB wild-type allele is located in the vicinity of 3q22.3 and is approximately 105 kb in length. This allele, which encodes… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2009
024619972009

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
PI3Ks (phosphoinositide 3-kinases) play a critical role in platelet functional responses. PI3Ks are activated upon P2Y12 receptor… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2010
2010
BACKGROUND Class IA PI 3-kinases produce phosphatidylinositol (3,4,5)-trisphosphate (PIP3). PIP3 is bound by AKT which facilities… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2009
2009
We have investigated the role of phosphoinositide 3-kinases (PI3Ks) in the in vitro pathophysiology of acute promyelocytic… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2008
Highly Cited
2008
On activation by receptors, the ubiquitously expressed class IA isoforms (p110α and p110β) of phosphatidylinositol-3-OH kinase… (More)
  • figure 2
  • figure 1
  • figure 3
  • table 1
Is this relevant?
2008
2008
PURPOSE The phosphoinositide 3-kinase (PI3K)/Akt pathway is frequently activated in human cancer and plays a crucial role in… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
RNA interference (RNAi) is a powerful tool to induce loss-of-function phenotypes by inhibiting gene expression post… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2002
2002
Although Gbetagamma is thought to mediate mitogen-activated protein kinase (MAPK) activation in response to G protein-coupled… (More)
Is this relevant?
2000
2000
Growth factors regulate a wide range of cellular processes via activation of the class-Ia phosphoinositide 3-kinases (PI 3… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • figure 6
Is this relevant?
2000
2000
Activation of p85/p110 type phosphatidylinositol kinase is essential for aspects of insulin-induced glucose metabolism, including… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Phosphoinositide 3-kinases (PI3Ks) are a family of lipid kinases that have been implicated in signal transduction through… (More)
Is this relevant?