Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

PF 1022A

Known as: Cyclo(D-2-hydroxypropanoyl-N-methyl-L-leucyl-3-phenyl-D-2-hydroxypropanoyl-N-methyl-L-leucyl-D-2-hydroxypropanoyl-N-methyl-L-leucyl-3-phenyl-D-2-hydroxypropanoyl-N-methyl-L-leucyl), PF-1022A, PF1022A 
 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Depsipeptides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Characterization of the Ca2+-Gated and Voltage-Dependent K+-Channel Slo-1 of Nematodes and Its Interaction with Emodepside
The cyclooctadepsipeptide emodepside and its parent compound PF1022A are broad-spectrum nematicidal drugs which are able to… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
2012
2012
Decreased emodepside sensitivity in unc-49 γ-aminobutyric acid (GABA)-receptor-deficient Caenorhabditis elegans.
Emodepside, a semi-synthetic derivative of PF1022A, belongs to a new class of anthelmintic drugs, the cyclooctadepsipeptides, and… Expand
Is this relevant?
2005
2005
Mechanisms of action of emodepside
The research of the class of cyclic octadepsipeptides started at the beginning of the 1990s. PF1022A, the starting material of… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Review
2003
Review
2003
Cyclooctadepsipeptides--an anthelmintically active class of compounds exhibiting a novel mode of action.
There are three major classes of anthelmintics for veterinary use: the benzimidazoles/prebenzimidazoles, the… Expand
Is this relevant?
Review
2002
Review
2002
PF1022A and related cyclodepsipeptides - a novel class of anthelmintics.
Parasitic nematodes are a major cause of morbidity and mortality in man and also cause widespread loss of food production by… Expand
Is this relevant?
2001
2001
Latrophilin-like receptor from the parasitic nematode Haemonchus contortus as target for the anthelmintic depsipeptide PF1022A.
SPECIFIC AIMSIn this study, we have tried to identify a possible protein target for PF1022A belonging to a new class of… Expand
Is this relevant?
2000
2000
In vivo activities of the new anthelmintic depsipeptide PF 1022A
Abstract PF 1022A is a member of a new class of cyclic depsipeptides with antiparasitic activity. Following in vitro and… Expand
  • table 1
  • table 2
  • figure 1
  • figure 3
  • figure 4
Is this relevant?
2000
2000
Biosynthesis of PF1022A and related cyclooctadepsipeptides.
PF1022A belongs to a recently identified class of N-methylated cyclooctadepsipeptides (CODPs) with strong anthelmintic properties… Expand
Is this relevant?
1998
1998
Effects of amorphous and polymorphs of PF1022A, a new antinematode drug, on Angiostrongylus costaricensis in mice.
To enhance the bioavailability of PF1022A (cyclo(D-lactyl-L-N-methylleucyl-D-3-phenyllactyl-L-N-met hylleucyl-D-lactyl-L-N… Expand
Is this relevant?
1996
1996
Characterization of subtypes of gamma-aminobutyric acid receptors in an Ascaris muscle preparation by binding assay and binding of PF1022A, a new anthelmintic, on the receptors
Abstract We examined the effect of PF1022A, one of the gabergic anthelmintics newly developed in Japan, on gamma-aminobutyric… Expand
  • figure 1
  • table 1
  • figure 2
  • table 2
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE