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PF 1022A

Known as: Cyclo(D-2-hydroxypropanoyl-N-methyl-L-leucyl-3-phenyl-D-2-hydroxypropanoyl-N-methyl-L-leucyl-D-2-hydroxypropanoyl-N-methyl-L-leucyl-3-phenyl-D-2-hydroxypropanoyl-N-methyl-L-leucyl), PF-1022A, PF1022A 
National Institutes of Health

Related topics

Related topics

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Broader (1)

Depsipeptides

Papers overview

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Review
2018
Review
2018
Structural Diversity and Biological Activities of Cyclic Depsipeptides from Fungi
Cyclic depsipeptides (CDPs) are cyclopeptides in which amide groups are replaced by corresponding lactone bonds due to the… 
2014
2014
Characterization of the Ca2+-Gated and Voltage-Dependent K+-Channel Slo-1 of Nematodes and Its Interaction with Emodepside
The cyclooctadepsipeptide emodepside and its parent compound PF1022A are broad-spectrum nematicidal drugs which are able to… 
Highly Cited
2005
Highly Cited
2005
Mechanisms of action of emodepside
The research of the class of cyclic octadepsipeptides started at the beginning of the 1990s. PF1022A, the starting material of… 
Review
2003
Review
2003
Cyclooctadepsipeptides--an anthelmintically active class of compounds exhibiting a novel mode of action.
Review
2002
Review
2002
PF1022A and related cyclodepsipeptides - a novel class of anthelmintics.
Parasitic nematodes are a major cause of morbidity and mortality in man and also cause widespread loss of food production by… 
Highly Cited
2001
Highly Cited
2001
Latrophilin‐like receptor from the parasitic nematode Haemonchus contortus as target for the anthelmintic depsipeptide PF1022A
PF1022A belongs to a new class of cyclodepsipeptides with broad anthelmintic activity. Here, we describe a novel target for… 
2001
2001
Azadepsipeptides: synthesis and evaluation of a novel class of peptidomimetics.
A general route to azadepsipeptides, a new class of pseudopeptides, has been established. The methodology was applied to the… 
2000
2000
In vivo activities of the new anthelmintic depsipeptide PF 1022A
Abstract PF 1022A is a member of a new class of cyclic depsipeptides with antiparasitic activity. Following in vitro and… 
1995
1995
Anthelmintic profile of the cyclodepsipeptide PF1022A in in vitro and in vivo models.
A novel cyclodepsipeptide of fungal origin, PF1022A, recently was reported to have anthelmintic activity. To supplement published… 
Highly Cited
1992
Highly Cited
1992
A new anthelmintic cyclodepsipeptide, PF1022A.
The novel anthelmintic cyclodepsipeptide PF1022A was isolated from cultured mycelia of Mycelia Sterilia PF1022 (FERM BP-2671). It… 
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